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Bone Marrow as a Hematopoietic Stem Cell Source for Gene Therapy in Sickle Cell Disease: Evidence from Rhesus and SCD Patients

Steady state bone marrow (BM) is the preferred hematopoietic stem cell (HSC) source for gene therapy in sickle cell disease (SCD) due to the recognized risk of vaso-occlusive crisis during granulocyte colony–stimulating factor mobilization. We previously established clinically relevant HSC gene tran...

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Bibliografski detalji
Izdano u:Hum Gene Ther Clin Dev
Glavni autori: Uchida, Naoya, Fujita, Atsushi, Hsieh, Matthew M., Bonifacino, Aylin C., Krouse, Allen E., Metzger, Mark E., Donahue, Robert E., Tisdale, John F.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695729/
https://ncbi.nlm.nih.gov/pubmed/28447889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/humc.2017.029
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