Avoidance of stimulation improves engraftment of cultured and retrovirally transduced hematopoietic cells in primates

Por Takatoku, Masaaki, Sellers, Stephanie, Agricola, Brian A., Metzger, Mark E., Kato, Ikunoshin, Donahue, Robert E., Dunbar, Cynthia E.
Publicado em 2001

Plerixafor (AMD3100) and granulocyte colony-stimulating factor (G-CSF) mobilize different CD34(+) cell populations based on global gene and microRNA expression signatures

Por Donahue, Robert E., Jin, Ping, Bonifacino, Aylin C., Metzger, Mark E., Ren, Jiaqiang, Wang, Ena, Stroncek, David F.
Publicado em 2009

Marking and Gene Expression by a Lentivirus Vector in Transplanted Human and Nonhuman Primate CD34(+) Cells

Por An, Dong Sung, Wersto, Robert P., Agricola, Brian A., Metzger, Mark E., Lu, Stephanie, Amado, Rafael G., Chen, Irvin S. Y., Donahue, Robert E.
Publicado em 2000

Thymidine Kinase Suicide Gene-mediated Ganciclovir Ablation of Autologous Gene-modified Rhesus Hematopoiesis

Por Barese, Cecilia N, Krouse, Allen E, Metzger, Mark E, King, Connor A, Traversari, Catia, Marini, Frank C, Donahue, Robert E, Dunbar, Cynthia E
Publicado em 2012

Peripheral blood stem cell transplants do not result in endometrial stromal engraftment

Por Wolff, Erin F., Uchida, Naoya, Donahue, Robert E., Metzger, Mark E., Hsieh, Matthew M., Libfraind, Lauren L., Hill, Micah J., Tisdale, John F.
Publicado em 2012

Paradoxical Drop in Circulating Neutrophil Count Following Granulocyte-Colony Stimulating Factor and Stem Cell Factor Administration in Rhesus Macaques: Rapid Neutrophil Decline Fo...

Por Gordon, Brent C., Revenis, Amy M., Bonifacino, Aylin C., Sander, William E., Metzger, Mark E., Krouse, Allen E., Usherson, Tatiana N., Donahue., Robert E.
Publicado em 2007

Development of a Human Immunodeficiency Virus Type 1-Based Lentiviral Vector That Allows Efficient Transduction of both Human and Rhesus Blood Cells

Por Uchida, Naoya, Washington, Kareem N., Hayakawa, Jun, Hsieh, Matthew M., Bonifacino, Aylin C., Krouse, Allen E., Metzger, Mark E., Donahue, Robert E., Tisdale, John F.
Publicado em 2009

Lentivirus Vector-Mediated Hematopoietic Stem Cell Gene Transfer of Common Gamma-Chain Cytokine Receptor in Rhesus Macaques

Por An, Dong Sung, Kung, Sam K. P., Bonifacino, Aylin, Wersto, Robert P., Metzger, Mark E., Agricola, Brian A., Mao, Si Hua, Chen, Irvin S. Y., Donahue, Robert E.
Publicado em 2001

Total body irradiation must be delivered at high dose for efficient engraftment and tolerance in a rhesus stem cell gene therapy model

Por Uchida, Naoya, Weitzel, R Patrick, Shvygin, Anna, Skala, Luke P, Raines, Lydia, Bonifacino, Aylin C, Krouse, Allen E, Metzger, Mark E, Donahue, Robert E, Tisdale, John F
Publicado no Mol Ther Methods Clin Dev (2016)

In Vitro Culture During Retroviral Transduction Improves Thymic Repopulation and Output After Total Body Irradiation and Autologous Peripheral Blood Progenitor Cell Transplantation...

Por Loré, Karin, Seggewiss, Ruth, Guenaga, F. Javier, Pittaluga, Stefania, Donahue, Robert E., Krouse, Allen, Metzger, Mark E., Koup, Richard A., Reilly, Cavan, Douek, Daniel C., Dunbar, Cynthia E.
Publicado em 2006

Significant mobilization of both conventional and regulatory T cells with AMD3100

Por Kean, Leslie S., Sen, Sharon, Onabajo, Olusegun, Singh, Karnail, Robertson, Jennifer, Stempora, Linda, Bonifacino, Aylin C., Metzger, Mark E., Promislow, Daniel E. L., Mattapallil, Joseph J., Donahue, Robert E.
Publicado em 2011

Integration-specific In Vitro Evaluation of Lentivirally Transduced Rhesus CD34(+) Cells Correlates With In Vivo Vector Copy Number

Por Uchida, Naoya, Evans, Molly E, Hsieh, Matthew M, Bonifacino, Aylin C, Krouse, Allen E, Metzger, Mark E, Sellers, Stephanie E, Dunbar, Cynthia E, Donahue, Robert E, Tisdale, John F
Publicado em 2013

Regulated Apoptosis of Genetically-Modified Hematopoietic Stem and Progenitor Cells via an Inducible Caspase-9 Suicide Gene in Rhesus Macaques

Por Barese, Cecilia N., Felizardo, Tania C., Sellers, Stephanie E., Keyvanfar, Keyvan, Di Stasi, Antonio, Metzger, Mark E., Krouse, Allen E., Donahue, Robert E., Spencer, David M., Dunbar, Cynthia E.
Publicado no Stem Cells (2015)

Pharmacological Modulation of Humoral Immunity in a Nonhuman Primate Model of AAV Gene Transfer for Hemophilia B

Por Mingozzi, Federico, Chen, Yifeng, Murphy, Samuel L, Edmonson, Shyrie C, Tai, Alex, Price, Sandra D, Metzger, Mark E, Zhou, Shangzhen, Wright, J Fraser, Donahue, Robert E, Dunbar, Cynthia E, High, Katherine A
Publicado em 2012

Accelerated Lymphocyte Reconstitution and Long-Term Recovery Following Transplantation of Lentiviral Transduced Rhesus CD34(+) Cells Mobilized by G-CSF and Plerixafor

Por Uchida, Naoya, Bonifacino, Aylin, Krouse, Allen E., Metzger, Mark E., Csako, Gyorgy, Lee-Stroka, Agnes, Fasano, Ross M., Leitman, Susan F., Mattapallil, Joseph J., Hsieh, Matthew M., Tisdale, John F., Donahue, Robert E.
Publicado em 2011

Dynamics of HSPC Repopulation In Non-human Primates Revealed by A Decade-Long Clonal-Tracking Study

Por Kim, Sanggu, Kim, Namshin, Presson, Angela P., Metzger, Mark E., Bonifacino, Aylin C., Sehl, Mary, Chow, Samson A., Crooks, Gay M., Dunbar, Cynthia E., An, Dong Sung, Donahue, Robert E., Chen, Irvin S.Y.
Publicado em 2014

Path to the clinic: Assessment of iPSC-based cell therapies in vivo in a non-human primate model

Por Hong, So Gun, Winkler, Thomas, Wu, Chuanfeng, Guo, Vicky, Pittaluga, Stefania, Nicolae, Alina, Donahue, Robert E., Metzger, Mark E., Price, Sandra D., Uchida, Naoya, Kuznetsov, Sergei A., Kilts, Tina, Li, Li, Robey, Pamela G., Dunbar, Cynthia E.
Publicado em 2014

Prostaglandin E2 enhances engraftment of human cord blood stem cells and shows long-term safety in preclinical non-human primate transplant models

Por Goessling, Wolfram, Allen, Robyn S, Guan, Xiao, Jin, Ping, Uchida, Naoya, Dovey, Michael, Harris, James M, Metzger, Mark E, Bonifacino, Aylin C, Stroncek, David, Stegner, Joseph, Armant, Myriam, Schlaeger, Thorsten, Tisdale, John F, Zon, Leonard I, Donahue, Robert E, North, Trista E
Publicado em 2011

High-efficiency Transduction of Rhesus Hematopoietic Repopulating Cells by a Modified HIV1-based Lentiviral Vector

Por Uchida, Naoya, Hargrove, Phillip W., Lap, Coen J., Evans, Molly E., Phang, Oswald, Bonifacino, Aylin C., Krouse, Allen E., Metzger, Mark E., Nguyen, Anh-Dao, Hsieh, Matthew M., Wolfsberg, Tyra G., Donahue, Robert E., Persons, Derek A., Tisdale, John F.
Publicado em 2012

Discordance in lymphoid tissue recovery following stem cell transplantation in rhesus macaques: an in vivo imaging study

Por Donahue, Robert E., Srinivasula, Sharat, Uchida, Naoya, Kim, Insook, St. Claire, Alexis, Duralde, Gorka, DeGrange, Paula, St. Claire, Marisa, Reba, Richard C., Bonifacino, Aylin C., Krouse, Allen E., Metzger, Mark E., Paik, Chang H., Lane, H. Clifford, Tisdale, John F., Di Mascio, Michele
Publicado no Blood (2015)