Accelerated Lymphocyte Reconstitution and Long-Term Recovery Following Transplantation of Lentiviral Transduced Rhesus CD34(+) Cells Mobilized by G-CSF and Plerixafor

OBJECTIVE: Granulocyte colony-stimulating factor (G-CSF) in combination with plerixafor produces significant mobilization of CD34(+) cells in rhesus macaques. We sought to evaluate whether these CD34(+) cells can stably reconstitute blood cells with lentiviral gene marking. METHODS: We performed hem...

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Main Authors: Uchida, Naoya, Bonifacino, Aylin, Krouse, Allen E., Metzger, Mark E., Csako, Gyorgy, Lee-Stroka, Agnes, Fasano, Ross M., Leitman, Susan F., Mattapallil, Joseph J., Hsieh, Matthew M., Tisdale, John F., Donahue, Robert E.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143244/
https://ncbi.nlm.nih.gov/pubmed/21549175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2011.04.002
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