Evaluation of engraftment and immunological tolerance after reduced intensity conditioning in a rhesus hematopoietic stem cell gene therapy model

Reduced intensity conditioning (RIC) is desirable for hematopoietic stem cell (HSC) targeted gene therapy; however, RIC may be insufficient for efficient engraftment and inducing immunological tolerance to transgenes. We previously established long-term gene marking in our rhesus macaque autologous...

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Detalhes bibliográficos
Publicado no:Gene Ther
Main Authors: Uchida, N, Weitzel, RP, Evans, ME, Green, R, Bonifacino, AC, Krouse, AE, Metzger, ME, Hsieh, MM, Donahue, RE, Tisdale, JF
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699286/
https://ncbi.nlm.nih.gov/pubmed/24257347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.67
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