A Symphony of Regulations Centered on p63 to Control Development of Ectoderm-Derived Structures

por Guerrini, Luisa, Costanzo, Antonio, Merlo, Giorgio R.
Publicado em 2011

Rho GTPases in Intellectual Disability: From Genetics to Therapeutic Opportunities

por Zamboni, Valentina, Jones, Rebecca, Umbach, Alessandro, Ammoni, Alessandra, Passafaro, Maria, Hirsch, Emilio, Merlo, Giorgio R.
Publicado no Int J Mol Sci (2018)

Neuronal Cytoskeleton in Intellectual Disability: From Systems Biology and Modeling to Therapeutic Opportunities

por Liaci, Carla, Camera, Mattia, Caslini, Giovanni, Rando, Simona, Contino, Salvatore, Romano, Valentino, Merlo, Giorgio R.
Publicado no Int J Mol Sci (2021)

Activation of the Wnt–βCatenin Pathway in a Cell Population on the Surface of the Forebrain Is Essential for the Establishment of Olfactory Axon Connections

por Zaghetto, Ambra A., Paina, Sara, Mantero, Stefano, Platonova, Natalia, Peretto, Paolo, Bovetti, Serena, Puche, Adam, Piccolo, Stefano, Merlo, Giorgio R.
Publicado em 2007

Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for...

por Garaffo, Giulia, Provero, Paolo, Molineris, Ivan, Pinciroli, Patrizia, Peano, Clelia, Battaglia, Cristina, Tomaiuolo, Daniela, Etzion, Talya, Gothilf, Yoav, Santoro, Massimo, Merlo, Giorgio R.
Publicado em 2013

The apical ectodermal ridge of the mouse model of ectrodactyly Dlx5;Dlx6(−/−) shows altered stratification and cell polarity, which are restored by exogenous Wnt5a ligand

por Conte, Daniele, Garaffo, Giulia, Lo Iacono, Nadia, Mantero, Stefano, Piccolo, Stefano, Cordenonsi, Michelangelo, Perez-Morga, David, Orecchia, Valeria, Poli, Valeria, Merlo, Giorgio R.
Publicado no Hum Mol Genet (2016)

Choice of Alternative Polyadenylation Sites, Mediated by the RNA-Binding Protein Elavl3, Plays a Role in Differentiation of Inhibitory Neuronal Progenitors

por Grassi, Elena, Santoro, Roberto, Umbach, Alessandro, Grosso, Anna, Oliviero, Salvatore, Neri, Francesco, Conti, Luciano, Ala, Ugo, Provero, Paolo, DiCunto, Ferdinando, Merlo, Giorgio R.
Publicado no Front Cell Neurosci (2019)

Wnt5a Is a Transcriptional Target of Dlx Homeogenes and Promotes Differentiation of Interneuron Progenitors In Vitro and In Vivo

por Paina, Sara, Garzotto, Donatella, DeMarchis, Silvia, Marino, Marco, Moiana, Alessia, Conti, Luciano, Cattaneo, Elena, Perera, Marzia, Corte, Giorgio, Calautti, Enzo, Merlo, Giorgio R.
Publicado no J Neurosci (2011)

The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation

por Chiabrando, Deborah, Marro, Samuele, Mercurio, Sonia, Giorgi, Carlotta, Petrillo, Sara, Vinchi, Francesca, Fiorito, Veronica, Fagoonee, Sharmila, Camporeale, Annalisa, Turco, Emilia, Merlo, Giorgio R., Silengo, Lorenzo, Altruda, Fiorella, Pinton, Paolo, Tolosano, Emanuela
Publicado em 2012

BMP-Mediated Functional Cooperation between Dlx5;Dlx6 and Msx1;Msx2 during Mammalian Limb Development

por Vieux-Rochas, Maxence, Bouhali, Kamal, Mantero, Stefano, Garaffo, Giulia, Provero, Paolo, Astigiano, Simonetta, Barbieri, Ottavia, Caratozzolo, Mariano F., Tullo, Apollonia, Guerrini, Luisa, Lallemand, Yvan, Robert, Benoît, Levi, Giovanni, Merlo, Giorgio R.
Publicado em 2013

The Dlx5 and Foxg1 transcription factors, linked via miRNA-9 and -200, are required for the development of the olfactory and GnRH system

por Garaffo, Giulia, Conte, Daniele, Provero, Paolo, Tomaiuolo, Daniela, Luo, Zheng, Pinciroli, Patrizia, Peano, Clelia, D'Atri, Ilaria, Gitton, Yorick, Etzion, Talya, Gothilf, Yoav, Gays, Dafne, Santoro, Massimo M., Merlo, Giorgio R.
Publicado no Mol Cell Neurosci (2015)

Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation

por Franco, Irene, Margaria, Jean Piero, De Santis, Maria Chiara, Ranghino, Andrea, Monteyne, Daniel, Chiaravalli, Marco, Pema, Monika, Campa, Carlo Cosimo, Ratto, Edoardo, Gulluni, Federico, Perez-Morga, David, Somlo, Stefan, Merlo, Giorgio R., Boletta, Alessandra, Hirsch, Emilio
Publicado no J Am Soc Nephrol (2016)

Hyperactivity of Rac1-GTPase pathway impairs neuritogenesis of cortical neurons by altering actin dynamics

por Zamboni, Valentina, Armentano, Maria, Berto, Gaia, Ciraolo, Elisa, Ghigo, Alessandra, Garzotto, Donatella, Umbach, Alessandro, DiCunto, Ferdinando, Parmigiani, Elena, Boido, Marina, Vercelli, Alessandro, El-Assawy, Nadia, Mauro, Alessandro, Priano, Lorenzo, Ponzoni, Luisa, Murru, Luca, Passafaro, Maria, Hirsch, Emilio, Merlo, Giorgio R.
Publicado no Sci Rep (2018)

PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function

por Franco, Irene, Gulluni, Federico, Campa, Carlo C., Costa, Carlotta, Margaria, Jean Piero, Ciraolo, Elisa, Martini, Miriam, Monteyne, Daniel, De Luca, Elisa, Germena, Giulia, Posor, York, Maffucci, Tania, Marengo, Stefano, Haucke, Volker, Falasca, Marco, Perez-Morga, David, Boletta, Alessandra, Merlo, Giorgio R., Hirsch, Emilio
Publicado em 2014

Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits

por Zamboni, Valentina, Armentano, Maria, Sarò, Gabriella, Ciraolo, Elisa, Ghigo, Alessandra, Germena, Giulia, Umbach, Alessandro, Valnegri, Pamela, Passafaro, Maria, Carabelli, Valentina, Gavello, Daniela, Bianchi, Veronica, D’Adamo, Patrizia, de Curtis, Ivan, El-Assawi, Nadia, Mauro, Alessandro, Priano, Lorenzo, Ferri, Nicola, Hirsch, Emilio, Merlo, Giorgio R.
Publicado no Sci Rep (2016)

Neuron-Derived Neurotrophic Factor Is Mutated in Congenital Hypogonadotropic Hypogonadism

por Messina, Andrea, Pulli, Kristiina, Santini, Sara, Acierno, James, Känsäkoski, Johanna, Cassatella, Daniele, Xu, Cheng, Casoni, Filippo, Malone, Samuel A., Ternier, Gaetan, Conte, Daniele, Sidis, Yisrael, Tommiska, Johanna, Vaaralahti, Kirsi, Dwyer, Andrew, Gothilf, Yoav, Merlo, Giorgio R., Santoni, Federico, Niederländer, Nicolas J., Giacobini, Paolo, Raivio, Taneli, Pitteloud, Nelly
Publicado no Am J Hum Genet (2020)