Phosphoinositides and disease

Por Falasca, Marco.
Publicado em 2012

3-Phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer

Por Fyffe, Chanse, Falasca, Marco
Publicado em 2013

Emerging role of the KRAS-PDK1 axis in pancreatic cancer

Por Ferro, Riccardo, Falasca, Marco
Publicado em 2014

Targeting p110gamma in gastrointestinal cancers: attack on multiple fronts

Por Falasca, Marco, Maffucci, Tania
Publicado em 2014

Diet and Pancreatic Cancer Prevention

Por Casari, Ilaria, Falasca, Marco
Publicado no Cancers (Basel) (2015)

Lysophosphatidylinositol Signalling and Metabolic Diseases

Por Arifin, Syamsul A., Falasca, Marco
Publicado no Metabolites (2016)

Novel roles for class II Phosphoinositide 3-Kinase C2β in signalling pathways involved in prostate cancer cell invasion

Por Mavrommati, Ioanna, Cisse, Ouma, Falasca, Marco, Maffucci, Tania
Publicado no Sci Rep (2016)

Epithelial-mesenchymal transition as a therapeutic target for overcoming chemoresistance in pancreatic cancer

Por Elaskalani, Omar, Razak, Norbaini Binti Abdol, Falasca, Marco, Metharom, Pat
Publicado no World J Gastrointest Oncol (2017)

Insulin induces phosphatidylinositol-3-phosphate formation through TC10 activation

Por Maffucci, Tania, Brancaccio, Anna, Piccolo, Enza, Stein, Robert C., Falasca, Marco
Publicado em 2003

A novel regulatory mechanism links PLCγ1 to PDK1

Por Raimondi, Claudio, Chikh, Anissa, Wheeler, Ann P., Maffucci, Tania, Falasca, Marco
Publicado em 2012

Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway

Por Edling, Charlotte E, Selvaggi, Federico, Ghonaim, Ragheda, Maffucci, Tania, Falasca, Marco
Publicado em 2014

A Novel Positive Feedback Loop Mediated by the Docking Protein Gab1 and Phosphatidylinositol 3-Kinase in Epidermal Growth Factor Receptor Signaling

Por Rodrigues, Gerard A., Falasca, Marco, Zhang, Zhongtao, Ong, Siew Hwa, Schlessinger, Joseph
Publicado em 2000

Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration

Por Maffucci, Tania, Cooke, Frank T., Foster, Fiona M., Traer, Colin J., Fry, Michael J., Falasca, Marco
Publicado em 2005

A Phosphoinositide 3-Kinase/Phospholipase Cgamma1 Pathway Regulates Fibroblast Growth Factor-Induced Capillary Tube Formation

Por Maffucci, Tania, Raimondi, Claudio, Abu-Hayyeh, Shadi, Dominguez, Veronica, Sala, Gianluca, Zachary, Ian, Falasca, Marco
Publicado em 2009

Class II Phosphoinositide 3-Kinases Contribute to Endothelial Cells Morphogenesis

Por Tibolla, Gianpaolo, Piñeiro, Roberto, Chiozzotto, Daniela, Mavrommati, Ioanna, Wheeler, Ann P., Norata, Giuseppe Danilo, Catapano, Alberico Luigi, Maffucci, Tania, Falasca, Marco
Publicado em 2013

Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer

Por Nesi, Giulia, Sestito, Simona, Mey, Valentina, Ricciardi, Simona, Falasca, Marco, Danesi, Romano, Lapucci, Annalina, Breschi, Maria C., Fogli, Stefano, Rapposelli, Simona
Publicado em 2013

CD31 signals confer immune privilege to the vascular endothelium

Por Cheung, Kenneth, Ma, Liang, Wang, Guosu, Coe, David, Ferro, Riccardo, Falasca, Marco, Buckley, Christopher D., Mauro, Claudio, Marelli-Berg, Federica M.
Publicado no Proc Natl Acad Sci U S A (2015)

A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion

Por Raimondi, Claudio, Calleja, Veronique, Ferro, Riccardo, Fantin, Alessandro, Riley, Andrew M., Potter, Barry V. L., Brennan, Caroline H., Maffucci, Tania, Larijani, Banafshé, Falasca, Marco
Publicado no Sci Rep (2016)

Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression

Por Chikh, Anissa, Ferro, Riccardo, Abbott, Jonathan J., Piñeiro, Roberto, Buus, Richard, Iezzi, Manuela, Ricci, Francesca, Bergamaschi, Daniele, Ostano, Paola, Chiorino, Giovanna, Lattanzio, Rossano, Broggini, Massimo, Piantelli, Mauro, Maffucci, Tania, Falasca, Marco
Publicado no Oncotarget (2016)

PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling

Por Braccini, Laura, Ciraolo, Elisa, Campa, Carlo C., Perino, Alessia, Longo, Dario L., Tibolla, Gianpaolo, Pregnolato, Marco, Cao, Yanyan, Tassone, Beatrice, Damilano, Federico, Laffargue, Muriel, Calautti, Enzo, Falasca, Marco, Norata, Giuseppe D., Backer, Jonathan M., Hirsch, Emilio
Publicado no Nat Commun (2015)