Targeting PI3K in Cancer: Any Good News?

nork Martini, Miriam, Ciraolo, Elisa, Gulluni, Federico, Hirsch, Emilio
Argitaratua 2013

Targeting PI3K/AKT/mTOR Signaling Pathway in Breast Cancer

nork Li, Huayi, Prever, Lorenzo, Hirsch, Emilio, Gulluni, Federico
Argitaratua izan da Cancers (Basel) (2021)

PI(3,4)P2 Signaling in Cancer and Metabolism

nork Gozzelino, Luca, De Santis, Maria Chiara, Gulluni, Federico, Hirsch, Emilio, Martini, Miriam
Argitaratua izan da Front Oncol (2020)

Downregulation of class II phosphoinositide 3-kinase PI3K-C2β delays cell division and potentiates the effect of docetaxel on cancer cell growth

nork Cisse, Ouma, Quraishi, Muzthahid, Gulluni, Federico, Guffanti, Federica, Mavrommati, Ioanna, Suthanthirakumaran, Methushaa, Oh, Lara C. R., Schlatter, Jessica N., Sarvananthan, Ambisha, Broggini, Massimo, Hirsch, Emilio, Falasca, Marco, Maffucci, Tania
Argitaratua izan da J Exp Clin Cancer Res (2019)

In vivo role of INPP4B in tumor and metastasis suppression through regulation of PI3K/AKT signaling at endosomes

nork Chew, Chen Li, Lunardi, Andrea, Gulluni, Federico, Ruan, Daniel T., Chen, Ming, Salmena, Leonardo, Nishino, Michiya, Papa, Antonella, Ng, Christopher, Fung, Jacqueline, Clohessy, John G., Sasaki, Junko, Sasaki, Takehiko, Bronson, Roderick T., Hirsch, Emilio, Pandolfi, Pier Paolo
Argitaratua izan da Cancer Discov (2015)

Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation

nork Franco, Irene, Margaria, Jean Piero, De Santis, Maria Chiara, Ranghino, Andrea, Monteyne, Daniel, Chiaravalli, Marco, Pema, Monika, Campa, Carlo Cosimo, Ratto, Edoardo, Gulluni, Federico, Perez-Morga, David, Somlo, Stefan, Merlo, Giorgio R., Boletta, Alessandra, Hirsch, Emilio
Argitaratua izan da J Am Soc Nephrol (2016)

PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function

nork Franco, Irene, Gulluni, Federico, Campa, Carlo C., Costa, Carlotta, Margaria, Jean Piero, Ciraolo, Elisa, Martini, Miriam, Monteyne, Daniel, De Luca, Elisa, Germena, Giulia, Posor, York, Maffucci, Tania, Marengo, Stefano, Haucke, Volker, Falasca, Marco, Perez-Morga, David, Boletta, Alessandra, Merlo, Giorgio R., Hirsch, Emilio
Argitaratua 2014

Mutations in PIK3C2A cause syndromic short stature, skeletal abnormalities, and cataracts associated with ciliary dysfunction

nork Tiosano, Dov, Baris, Hagit N., Chen, Anlu, Hitzert, Marrit M., Schueler, Markus, Gulluni, Federico, Wiesener, Antje, Bergua, Antonio, Mory, Adi, Copeland, Brett, Gleeson, Joseph G., Rump, Patrick, van Meer, Hester, Sival, Deborah A., Haucke, Volker, Kriwinsky, Josh, Knaup, Karl X., Reis, André, Hauer, Nadine N., Hirsch, Emilio, Roepman, Ronald, Pfundt, Rolph, Thiel, Christian T., Wiesener, Michael S., Aslanyan, Mariam G., Buchner, David A.
Argitaratua izan da PLoS Genet (2019)

PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation

nork Gulluni, Federico, Prever, Lorenzo, Li, Huayi, Krafcikova, Petra, Corrado, Ilaria, Lo, Wen-Ting, Margaria, Jean Piero, Chen, Anlu, De Santis, Maria Chiara, Cnudde, Sophie J., Fogerty, Joseph, Yuan, Alex, Massarotti, Alberto, Sarijalo, Nasrin Torabi, Vadas, Oscar, Williams, Roger L., Thelen, Marcus, Powell, David R., Schüler, Markus, Wiesener, Michael S., Balla, Tamas, Baris, Hagit N., Tiosano, Dov, McDermott, Brian M., Perkins, Brian D., Ghigo, Alessandra, Martini, Miriam, Haucke, Volker, Boura, Evzen, Merlo, Giorgio Roberto, Buchner, David A., Hirsch, Emilio
Argitaratua izan da Science (2021)