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Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation

Signaling from the primary cilium regulates kidney tubule development and cyst formation. However, the mechanism controlling targeting of ciliary components necessary for cilium morphogenesis and signaling is largely unknown. Here, we studied the function of class II phosphoinositide 3-kinase-C2α (P...

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書誌詳細
出版年:J Am Soc Nephrol
主要な著者: Franco, Irene, Margaria, Jean Piero, De Santis, Maria Chiara, Ranghino, Andrea, Monteyne, Daniel, Chiaravalli, Marco, Pema, Monika, Campa, Carlo Cosimo, Ratto, Edoardo, Gulluni, Federico, Perez-Morga, David, Somlo, Stefan, Merlo, Giorgio R., Boletta, Alessandra, Hirsch, Emilio
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Nephrology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814170/
https://ncbi.nlm.nih.gov/pubmed/26271513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014100967
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