Class II PI3Ks at the Intersection between Signal Transduction and Membrane Trafficking

Por Margaria, Jean Piero, Ratto, Edoardo, Gozzelino, Luca, Li, Huayi, Hirsch, Emilio
Publicado no Biomolecules (2019)

The Guareschi Pyridine Scaffold as a Valuable Platform for the Identification of Selective PI3K Inhibitors

Por Galli, Ubaldina, Ciraolo, Elisa, Massarotti, Alberto, Margaria, Jean Piero, Sorba, Giovanni, Hirsch, Emilio, Tron, Gian Cesare
Publicado no Molecules (2015)

Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5

Por Jenkins, Meredith L., Margaria, Jean Piero, Stariha, Jordan T. B., Hoffmann, Reece M., McPhail, Jacob A., Hamelin, David J., Boulanger, Martin J., Hirsch, Emilio, Burke, John E.
Publicado no Nat Commun (2018)

A Novel Multiplex qRT-PCR Assay to Detect SARS-CoV-2 Infection: High Sensitivity and Increased Testing Capacity

Por Petrillo, Sara, Carrà, Giovanna, Bottino, Paolo, Zanotto, Elisa, De Santis, Maria Chiara, Margaria, Jean Piero, Giorgio, Alessandro, Mandili, Giorgia, Martini, Miriam, Cavallo, Rossana, Barberio, Davide, Altruda, Fiorella
Publicado no Microorganisms (2020)

Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation

Por Franco, Irene, Margaria, Jean Piero, De Santis, Maria Chiara, Ranghino, Andrea, Monteyne, Daniel, Chiaravalli, Marco, Pema, Monika, Campa, Carlo Cosimo, Ratto, Edoardo, Gulluni, Federico, Perez-Morga, David, Somlo, Stefan, Merlo, Giorgio R., Boletta, Alessandra, Hirsch, Emilio
Publicado no J Am Soc Nephrol (2016)

Identification of a Potent Phosphoinositide 3‐Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs

Por Pirali, Tracey, Ciraolo, Elisa, Aprile, Silvio, Massarotti, Alberto, Berndt, Alex, Griglio, Alessia, Serafini, Marta, Mercalli, Valentina, Landoni, Clarissa, Campa, Carlo Cosimo, Margaria, Jean Piero, Silva, Rangel L., Grosa, Giorgio, Sorba, Giovanni, Williams, Roger, Hirsch, Emilio, Tron, Gian Cesare
Publicado no ChemMedChem (2017)

PI3K Class II α Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function

Por Franco, Irene, Gulluni, Federico, Campa, Carlo C., Costa, Carlotta, Margaria, Jean Piero, Ciraolo, Elisa, Martini, Miriam, Monteyne, Daniel, De Luca, Elisa, Germena, Giulia, Posor, York, Maffucci, Tania, Marengo, Stefano, Haucke, Volker, Falasca, Marco, Perez-Morga, David, Boletta, Alessandra, Merlo, Giorgio R., Hirsch, Emilio
Publicado em 2014

PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation

Por Gulluni, Federico, Prever, Lorenzo, Li, Huayi, Krafcikova, Petra, Corrado, Ilaria, Lo, Wen-Ting, Margaria, Jean Piero, Chen, Anlu, De Santis, Maria Chiara, Cnudde, Sophie J., Fogerty, Joseph, Yuan, Alex, Massarotti, Alberto, Sarijalo, Nasrin Torabi, Vadas, Oscar, Williams, Roger L., Thelen, Marcus, Powell, David R., Schüler, Markus, Wiesener, Michael S., Balla, Tamas, Baris, Hagit N., Tiosano, Dov, McDermott, Brian M., Perkins, Brian D., Ghigo, Alessandra, Martini, Miriam, Haucke, Volker, Boura, Evzen, Merlo, Giorgio Roberto, Buchner, David A., Hirsch, Emilio
Publicado no Science (2021)