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Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5
The GTPase Rab11 plays key roles in receptor recycling, oogenesis, autophagosome formation, and ciliogenesis. However, investigating Rab11 regulation has been hindered by limited molecular detail describing activation by cognate guanine nucleotide exchange factors (GEFs). Here, we present the struct...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6138693/ https://ncbi.nlm.nih.gov/pubmed/30217979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06196-z |
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