Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB

Small G-proteins of the Ras superfamily control the temporal and spatial coordination of intracellular signaling networks by acting as molecular on/off switches. Guanine nucleotide exchange factors (GEFs) regulate the activation of these G-proteins through catalytic replacement of GDP by GTP. During...

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Autores principales: Guo, Zhong, Hou, Xiaomin, Goody, Roger S., Itzen, Aymelt
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Membrane Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820881/
https://ncbi.nlm.nih.gov/pubmed/24072714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.498329
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