GDP-bound and Nucleotide-free Intermediates of the Guanine Nucleotide Exchange in the Rab5·Vps9 System

Many GTPases regulate intracellular transport and signaling in eukaryotes. Guanine nucleotide exchange factors (GEFs) activate GTPases by catalyzing the exchange of their GDP for GTP. Here we present crystallographic and biochemical studies of a GEF reaction with four crystal structures of Arabidops...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Uejima, Tamami, Ihara, Kentaro, Goh, Tatsuaki, Ito, Emi, Sunada, Mariko, Ueda, Takashi, Nakano, Akihiko, Wakatsuki, Soichi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2010
विषय:
Protein Structure and Folding
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978598/
https://ncbi.nlm.nih.gov/pubmed/20833725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.152132
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