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The substrate specificity of the human TRAPPII complex’s Rab-guanine nucleotide exchange factor activity

The TRAnsport Protein Particle (TRAPP) complexes act as Guanine nucleotide exchange factors (GEFs) for Rab GTPases, which are master regulators of membrane trafficking in eukaryotic cells. In metazoans, there are two large multi-protein TRAPP complexes: TRAPPII and TRAPPIII, with the TRAPPII complex...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Jenkins, Meredith L., Harris, Noah J., Dalwadi, Udit, Fleming, Kaelin D., Ziemianowicz, Daniel S., Rafiei, Atefeh, Martin, Emily M., Schriemer, David C., Yip, Calvin K., Burke, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719173/
https://ncbi.nlm.nih.gov/pubmed/33277614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01459-2
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