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PI(3,4)P2 Signaling in Cancer and Metabolism
The phosphatidylinositide 3 kinases (PI3Ks) and their downstream mediators AKT and mammalian target of rapamycin (mTOR) are central regulators of glycolysis, cancer metabolism, and cancer cell proliferation. At the molecular level, PI3K signaling involves the generation of the second messenger lipid...
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| 出版年: | Front Oncol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7136497/ https://ncbi.nlm.nih.gov/pubmed/32296634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00360 |
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