The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation

Feline leukemia virus subgroup C receptor 1 (FLVCR1) is a cell membrane heme exporter that maintains the balance between heme levels and globin synthesis in erythroid precursors. It was previously shown that Flvcr1-null mice died in utero due to a failure of erythropoiesis. Here, we identify Flvcr1b...

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Autors principals: Chiabrando, Deborah, Marro, Samuele, Mercurio, Sonia, Giorgi, Carlotta, Petrillo, Sara, Vinchi, Francesca, Fiorito, Veronica, Fagoonee, Sharmila, Camporeale, Annalisa, Turco, Emilia, Merlo, Giorgio R., Silengo, Lorenzo, Altruda, Fiorella, Pinton, Paolo, Tolosano, Emanuela
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533534/
https://ncbi.nlm.nih.gov/pubmed/23187127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62422
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