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Hemopexin Prevents Endothelial Damage and Liver Congestion in a Mouse Model of Heme Overload

Intravascular hemolysis results in the release of massive amounts of hemoglobin and heme into plasma, where they are rapidly bound by haptoglobin and hemopexin, respectively. Data from haptoglobin and hemopexin knockout mice have shown that both proteins protect from renal damage after phenylhydrazi...

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Detalhes bibliográficos
Main Authors: Vinchi, Francesca, Gastaldi, Stefania, Silengo, Lorenzo, Altruda, Fiorella, Tolosano, Emanuela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438305/
https://ncbi.nlm.nih.gov/pubmed/18556779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071130
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