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Hemopexin Prevents Endothelial Damage and Liver Congestion in a Mouse Model of Heme Overload

Intravascular hemolysis results in the release of massive amounts of hemoglobin and heme into plasma, where they are rapidly bound by haptoglobin and hemopexin, respectively. Data from haptoglobin and hemopexin knockout mice have shown that both proteins protect from renal damage after phenylhydrazi...

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Hlavní autoři: Vinchi, Francesca, Gastaldi, Stefania, Silengo, Lorenzo, Altruda, Fiorella, Tolosano, Emanuela
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438305/
https://ncbi.nlm.nih.gov/pubmed/18556779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071130
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