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Heme–hemopexin complex attenuates neuronal cell death and stroke damage

Hemoproteins undergo degradation during hypoxic/ischemic conditions, but the pro-oxidant free heme that is released cannot be recycled and must be degraded. The extracellular heme associates with its high-affinity binding protein, hemopexin (HPX). Hemopexin is shown here to be expressed by cortical...

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Podrobná bibliografie
Vydáno v:J Cereb Blood Flow Metab
Hlavní autoři: Li, Rung-chi, Saleem, Sofiyan, Zhen, Gehua, Cao, Wangsen, Zhuang, Hean, Lee, Jongseok, Smith, Ann, Altruda, Fiorella, Tolosano, Emanuela, Doré, Sylvain
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015738/
https://ncbi.nlm.nih.gov/pubmed/19277051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.19
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