Hemopexin Prevents Endothelial Damage and Liver Congestion in a Mouse Model of Heme Overload

Intravascular hemolysis results in the release of massive amounts of hemoglobin and heme into plasma, where they are rapidly bound by haptoglobin and hemopexin, respectively. Data from haptoglobin and hemopexin knockout mice have shown that both proteins protect from renal damage after phenylhydrazi...

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Bibliografiske detaljer
Main Authors: Vinchi, Francesca, Gastaldi, Stefania, Silengo, Lorenzo, Altruda, Fiorella, Tolosano, Emanuela
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2008
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438305/
https://ncbi.nlm.nih.gov/pubmed/18556779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071130
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