ChIPping away at gene regulation

door Massie, Charles E, Mills, Ian G
Gepubliceerd in 2008

New androgen receptor genomic targets show an interaction with the ETS1 transcription factor

door Massie, Charles E, Adryan, Boris, Barbosa-Morais, Nuno L, Lynch, Andy G, Tran, Maxine G, Neal, David E, Mills, Ian G
Gepubliceerd in 2007

Nongenetic stochastic expansion of JAK2V617F-homozygous subclones in polycythemia vera?

door Godfrey, Anna L., Nangalia, Jyoti, Baxter, E. Joanna, Massie, Charles E., Kent, David G., Papaemmanuil, Elli, Campbell, Peter J., Green, Anthony R.
Gepubliceerd in Blood (2014)

Epigenetic and oncogenic regulation of SLC16A7 (MCT2) results in protein over-expression, impacting on signalling and cellular phenotypes in prostate cancer

door Pertega-Gomes, Nelma, Vizcaino, Jose R., Felisbino, Sergio, Warren, Anne Y., Shaw, Greg, Kay, Jonathan, Whitaker, Hayley, Lynch, Andy G., Fryer, Lee, Neal, David E., Massie, Charles E.
Gepubliceerd in Oncotarget (2015)

HES5 silencing is an early and recurrent change in prostate tumourigenesis

door Massie, Charles E, Spiteri, Inmaculada, Ross-Adams, Helen, Luxton, Hayley, Kay, Jonathan, Whitaker, Hayley C, Dunning, Mark J, Lamb, Alastair D, Ramos-Montoya, Antonio, Brewer, Daniel S, Cooper, Colin S, Eeles, Rosalind, Warren, Anne Y, Tavaré, Simon, Neal, David E, Lynch, Andy G
Gepubliceerd in Endocr Relat Cancer (2015)

STAT1 activation in association with JAK2 exon 12 mutations

door Godfrey, Anna L., Chen, Edwin, Massie, Charles E., Silber, Yvonne, Pagano, Francesca, Bellosillo, Beatriz, Guglielmelli, Paola, Harrison, Claire N., Reilly, John T., Stegelmann, Frank, Bijou, Fontanet, Lippert, Eric, Boiron, Jean-Michel, Döhner, Konstanze, Vannucchi, Alessandro M., Besses, Carlos, Green, Anthony R.
Gepubliceerd in Haematologica (2016)

Implementing liquid biopsies into clinical decision making for cancer immunotherapy

door Quandt, Dagmar, Zucht, Hans Dieter, Amann, Arno, Wulf-Goldenberg, Anne, Borrebaeck, Carl, Cannarile, Michael, Lambrechts, Diether, Oberacher, Herbert, Garrett, James, Nayak, Tapan, Kazinski, Michael, Massie, Charles, Schwarzenbach, Heidi, Maio, Michele, Prins, Robert, Wendik, Björn, Hockett, Richard, Enderle, Daniel, Noerholm, Mikkel, Hendriks, Hans, Zwierzina, Heinz, Seliger, Barbara
Gepubliceerd in Oncotarget (2017)

Inactivating CUX1 mutations promote tumorigenesis

door Wong, Chi C., Martincorena, Inigo, Rust, Alistair G., Rashid, Mamunur, Alifrangis, Constantine, Alexandrov, Ludmil B., Tiffen, Jessamy C., Kober, Christina, Green, Anthony R., Massie, Charles E., Nangalia, Jyoti, Lempidaki, Stella, Döhner, Hartmut, Döhner, Konstanze, Bray, Sarah J., McDermott, Ultan, Papaemmanuil, Elli, Campbell, Peter J., Adams, David J.
Gepubliceerd in 2013

Effect of Mutation Order on Myeloproliferative Neoplasms

door Ortmann, Christina A., Kent, David G., Nangalia, Jyoti, Silber, Yvonne, Wedge, David C., Grinfeld, Jacob, Baxter, E. Joanna, Massie, Charles E., Papaemmanuil, Elli, Menon, Suraj, Godfrey, Anna L., Dimitropoulou, Danai, Guglielmelli, Paola, Bellosillo, Beatriz, Besses, Carles, Döhner, Konstanze, Harrison, Claire N., Vassiliou, George S., Vannucchi, Alessandro, Campbell, Peter J., Green, Anthony R.
Gepubliceerd in N Engl J Med (2015)

The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis

door Massie, Charles E, Lynch, Andy, Ramos-Montoya, Antonio, Boren, Joan, Stark, Rory, Fazli, Ladan, Warren, Anne, Scott, Helen, Madhu, Basetti, Sharma, Naomi, Bon, Helene, Zecchini, Vinny, Smith, Donna-Michelle, DeNicola, Gina M, Mathews, Nik, Osborne, Michelle, Hadfield, James, MacArthur, Stewart, Adryan, Boris, Lyons, Scott K, Brindle, Kevin M, Griffiths, John, Gleave, Martin E, Rennie, Paul S, Neal, David E, Mills, Ian G
Gepubliceerd in 2011

HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer

door Ross-Adams, Helen, Ball, Stephen, Lawrenson, Kate, Halim, Silvia, Russell, Roslin, Wells, Claire, Strand, Siri H., Ørntoft, Torben F., Larson, Melissa, Armasu, Sebastian, Massie, Charles E., Asim, Mohammad, Mortensen, Martin M., Borre, Michael, Woodfine, Kathryn, Warren, Anne Y., Lamb, Alastair D., Kay, Jonathan, Whitaker, Hayley, Ramos-Montoya, Antonio, Murrell, Adele, Sørensen, Karina D., Fridley, Brooke L., Goode, Ellen L., Gayther, Simon A., Masters, John, Neal, David E., Mills, Ian G.
Gepubliceerd in Oncotarget (2016)

Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer

door Asim, Mohammad, Tarish, Firas, Zecchini, Heather I., Sanjiv, Kumar, Gelali, Eleni, Massie, Charles E., Baridi, Ajoeb, Warren, Anne Y., Zhao, Wanfeng, Ogris, Christoph, McDuffus, Leigh-Anne, Mascalchi, Patrice, Shaw, Greg, Dev, Harveer, Wadhwa, Karan, Wijnhoven, Paul, Forment, Josep V., Lyons, Scott R., Lynch, Andy G., O’Neill, Cormac, Zecchini, Vincent R., Rennie, Paul S., Baniahmad, Aria, Tavaré, Simon, Mills, Ian G., Galanty, Yaron, Crosetto, Nicola, Schultz, Niklas, Neal, David, Helleday, Thomas
Gepubliceerd in Nat Commun (2017)

Comprehensive characterization of cell-free tumor DNA in plasma and urine of patients with renal tumors

door Smith, Christopher G., Moser, Tina, Mouliere, Florent, Field-Rayner, Johanna, Eldridge, Matthew, Riediger, Anja L., Chandrananda, Dineika, Heider, Katrin, Wan, Jonathan C. M., Warren, Anne Y., Morris, James, Hudecova, Irena, Cooper, Wendy N., Mitchell, Thomas J., Gale, Davina, Ruiz-Valdepenas, Andrea, Klatte, Tobias, Ursprung, Stephan, Sala, Evis, Riddick, Antony C. P., Aho, Tevita F., Armitage, James N., Perakis, Samantha, Pichler, Martin, Seles, Maximilian, Wcislo, Gabriel, Welsh, Sarah J., Matakidou, Athena, Eisen, Tim, Massie, Charles E., Rosenfeld, Nitzan, Heitzer, Ellen, Stewart, Grant D.
Gepubliceerd in Genome Med (2020)

Enhanced detection of circulating tumor DNA by fragment size analysis

door Mouliere, Florent, Chandrananda, Dineika, Piskorz, Anna M., Moore, Elizabeth K., Morris, James, Ahlborn, Lise Barlebo, Mair, Richard, Goranova, Teodora, Marass, Francesco, Heider, Katrin, Wan, Jonathan C. M., Supernat, Anna, Hudecova, Irena, Gounaris, Ioannis, Ros, Susana, Jimenez-Linan, Mercedes, Garcia-Corbacho, Javier, Patel, Keval, Østrup, Olga, Murphy, Suzanne, Eldridge, Matthew D., Gale, Davina, Stewart, Grant D., Burge, Johanna, Cooper, Wendy N., van der Heijden, Michiel S., Massie, Charles E., Watts, Colin, Corrie, Pippa, Pacey, Simon, Brindle, Kevin, Baird, Richard D., Mau-Sørensen, Morten, Parkinson, Christine A., Smith, Christopher G., Brenton, James D., Rosenfeld, Nitzan
Gepubliceerd in Sci Transl Med (2018)

Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target

door Asim, Mohammad, Massie, Charles E., Orafidiya, Folake, Pértega-Gomes, Nelma, Warren, Anne Y., Esmaeili, Mohsen, Selth, Luke A., Zecchini, Heather I., Luko, Katarina, Qureshi, Arham, Baridi, Ajoeb, Menon, Suraj, Madhu, Basetti, Escriu, Carlos, Lyons, Scott, Vowler, Sarah L., Zecchini, Vincent R., Shaw, Greg, Hessenkemper, Wiebke, Russell, Roslin, Mohammed, Hisham, Stefanos, Niki, Lynch, Andy G., Grigorenko, Elena, D’Santos, Clive, Taylor, Chris, Lamb, Alastair, Sriranjan, Rouchelle, Yang, Jiali, Stark, Rory, Dehm, Scott M., Rennie, Paul S., Carroll, Jason S., Griffiths, John R., Tavaré, Simon, Mills, Ian G., McEwan, Iain J., Baniahmad, Aria, Tilley, Wayne D., Neal, David E.
Gepubliceerd in J Natl Cancer Inst (2015)

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

door Ju, Young Seok, Alexandrov, Ludmil B, Gerstung, Moritz, Martincorena, Inigo, Nik-Zainal, Serena, Ramakrishna, Manasa, Davies, Helen R, Papaemmanuil, Elli, Gundem, Gunes, Shlien, Adam, Bolli, Niccolo, Behjati, Sam, Tarpey, Patrick S, Nangalia, Jyoti, Massie, Charles E, Butler, Adam P, Teague, Jon W, Vassiliou, George S, Green, Anthony R, Du, Ming-Qing, Unnikrishnan, Ashwin, Pimanda, John E, Teh, Bin Tean, Munshi, Nikhil, Greaves, Mel, Vyas, Paresh, El-Naggar, Adel K, Santarius, Tom, Collins, V Peter, Grundy, Richard, Taylor, Jack A, Hayes, D Neil, Malkin, David, Foster, Christopher S, Warren, Anne Y, Whitaker, Hayley C, Brewer, Daniel, Eeles, Rosalind, Cooper, Colin, Neal, David, Visakorpi, Tapio, Isaacs, William B, Bova, G Steven, Flanagan, Adrienne M, Futreal, P Andrew, Lynch, Andy G, Chinnery, Patrick F, McDermott, Ultan, Stratton, Michael R, Campbell, Peter J
Gepubliceerd in eLife (2014)