Single-molecule genomic data delineate patient-specific tumor profiles and cancer stem cell organization

Autor Sottoriva, Andrea, Spiteri, Inmaculada, Shibata, Darryl, Curtis, Christina, Tavaré, Simon
Vydáno 2012

Current Challenges in Glioblastoma: Intratumour Heterogeneity, Residual Disease, and Models to Predict Disease Recurrence

Autor Ellis, Hayley P., Greenslade, Mark, Powell, Ben, Spiteri, Inmaculada, Sottoriva, Andrea, Kurian, Kathreena M.
Vydáno v Front Oncol (2015)

Extent of differential allelic expression of candidate breast cancer genes is similar in blood and breast

Autor Maia, Ana-Teresa, Spiteri, Inmaculada, Lee, Alvin JX, O'Reilly, Martin, Jones, Linda, Caldas, Carlos, Ponder, Bruce AJ
Vydáno 2009

CD15 Expression Does Not Identify a Phenotypically or Genetically Distinct Glioblastoma Population

Autor Kenney-Herbert, Emma, Al-Mayhani, Talal, Piccirillo, Sara G.M., Fowler, Joanna, Spiteri, Inmaculada, Jones, Philip, Watts, Colin
Vydáno v Stem Cells Transl Med (2015)

Chemical Entities of Biological Interest: an update

Autor de Matos, Paula, Alcántara, Rafael, Dekker, Adriano, Ennis, Marcus, Hastings, Janna, Haug, Kenneth, Spiteri, Inmaculada, Turner, Steve, Steinbeck, Christoph
Vydáno 2010

Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics

Autor Sottoriva, Andrea, Spiteri, Inmaculada, Piccirillo, Sara G. M., Touloumis, Anestis, Collins, V. Peter, Marioni, John C., Curtis, Christina, Watts, Colin, Tavaré, Simon
Vydáno 2013

PMC42, a breast progenitor cancer cell line, has normal-like mRNA and microRNA transcriptomes

Autor Git, Anna, Spiteri, Inmaculada, Blenkiron, Cherie, Dunning, Mark J, Pole, Jessica CM, Chin, Suet-Feung, Wang, Yanzhong, Smith, James, Livesey, Frederick J, Caldas, Carlos
Vydáno 2008

The pitfalls of platform comparison: DNA copy number array technologies assessed

Autor Curtis, Christina, Lynch, Andy G, Dunning, Mark J, Spiteri, Inmaculada, Marioni, John C, Hadfield, James, Chin, Suet-Feung, Brenton, James D, Tavaré, Simon, Caldas, Carlos
Vydáno 2009

Saliva samples are a viable alternative to blood samples as a source of DNA for high throughput genotyping

Autor Abraham, Jean E, Maranian, Mel J, Spiteri, Inmaculada, Russell, Roslin, Ingle, Susan, Luccarini, Craig, Earl, Helena M, Pharoah, Paul PD, Dunning, Alison M, Caldas, Carlos
Vydáno 2012

Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking

Autor Cresswell, George D., Nichol, Daniel, Spiteri, Inmaculada, Tari, Haider, Zapata, Luis, Heide, Timon, Maley, Carlo C., Magnani, Luca, Schiavon, Gaia, Ashworth, Alan, Barry, Peter, Sottoriva, Andrea
Vydáno v Nat Commun (2020)

Characterisation of microRNA expression in post-natal mouse mammary gland development

Autor Avril-Sassen, Stefanie, Goldstein, Leonard D, Stingl, John, Blenkiron, Cherie, Le Quesne, John, Spiteri, Inmaculada, Karagavriilidou, Konstantina, Watson, Christine J, Tavaré, Simon, Miska, Eric A, Caldas, Carlos
Vydáno 2009

Identification of Genes Involved in Resistance to Interferon-α in Cutaneous T-Cell Lymphoma

Autor Tracey, Lorraine, Villuendas, Raquel, Ortiz, Pablo, Dopazo, Ana, Spiteri, Inmaculada, Lombardia, Luis, Rodríguez-Peralto, Jose L., Fernández-Herrera, Jesús, Hernández, Almudena, Fraga, Javier, Dominguez, Orlando, Herrero, Javier, Alonso, Miguel A., Dopazo, Joaquin, Piris, Miguel A.
Vydáno 2002

MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype

Autor Blenkiron, Cherie, Goldstein, Leonard D, Thorne, Natalie P, Spiteri, Inmaculada, Chin, Suet-Feung, Dunning, Mark J, Barbosa-Morais, Nuno L, Teschendorff, Andrew E, Green, Andrew R, Ellis, Ian O, Tavaré, Simon, Caldas, Carlos, Miska, Eric A
Vydáno 2007

Contributions to drug resistance in glioblastoma derived from malignant cells in the sub-ependymal zone

Autor Piccirillo, Sara GM, Spiteri, Inmaculada, Sottoriva, Andrea, Touloumis, Anestis, Ber, Suzan, Price, Stephen J, Heywood, Richard, Francis, Nicola-Jane, Howarth, Karen D, Collins, Vincent P, Venkitaraman, Ashok R, Curtis, Christina, Marioni, John C, Tavaré, Simon, Watts, Colin
Vydáno v Cancer Res (2014)

Measuring single cell divisions in human tissues from multi-region sequencing data

Autor Werner, Benjamin, Case, Jack, Williams, Marc J., Chkhaidze, Ketevan, Temko, Daniel, Fernández-Mateos, Javier, Cresswell, George D., Nichol, Daniel, Cross, William, Spiteri, Inmaculada, Huang, Weini, Tomlinson, Ian P. M., Barnes, Chris P., Graham, Trevor A., Sottoriva, Andrea
Vydáno v Nat Commun (2020)

HES5 silencing is an early and recurrent change in prostate tumourigenesis

Autor Massie, Charles E, Spiteri, Inmaculada, Ross-Adams, Helen, Luxton, Hayley, Kay, Jonathan, Whitaker, Hayley C, Dunning, Mark J, Lamb, Alastair D, Ramos-Montoya, Antonio, Brewer, Daniel S, Cooper, Colin S, Eeles, Rosalind, Warren, Anne Y, Tavaré, Simon, Neal, David E, Lynch, Andy G
Vydáno v Endocr Relat Cancer (2015)

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer

Autor Acar, Ahmet, Nichol, Daniel, Fernandez-Mateos, Javier, Cresswell, George D., Barozzi, Iros, Hong, Sung Pil, Trahearn, Nicholas, Spiteri, Inmaculada, Stubbs, Mark, Burke, Rosemary, Stewart, Adam, Caravagna, Giulio, Werner, Benjamin, Vlachogiannis, Georgios, Maley, Carlo C., Magnani, Luca, Valeri, Nicola, Banerji, Udai, Sottoriva, Andrea
Vydáno v Nat Commun (2020)

The spatio-temporal evolution of lymph node spread in early breast cancer

Autor Barry, Peter, Vatsiou, Alexandra, Spiteri, Inmaculada, Nichol, Daniel, Cresswell, George D., Acar, Ahmet, Trahearn, Nicholas, Hrebien, Sarah, Garcia-Murillas, Isaac, Chkhaidze, Kate, Ermini, Luca, Huntingford, Ian Said, Cottom, Hannah, Zabaglo, Lila, Koelble, Konrad, Khalique, Saira, Rusby, Jennifer, Muscara, Francesca, Dowsett, Mitch, Maley, Carlo, Natrajan, Rachael, Yuan, Yinyin, Schiavon, Gaia, Turner, Nicholas, Sottoriva, Andrea
Vydáno v Clin Cancer Res (2018)

Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype

Autor Lupo, Barbara, Sassi, Francesco, Pinnelli, Marika, Galimi, Francesco, Zanella, Eugenia R., Vurchio, Valentina, Migliardi, Giorgia, Gagliardi, Paolo Armando, Puliafito, Alberto, Manganaro, Daria, Luraghi, Paolo, Kragh, Michael, Pedersen, Mikkel W., Horak, Ivan D., Boccaccio, Carla, Medico, Enzo, Primo, Luca, Nichol, Daniel, Spiteri, Inmaculada, Heide, Timon, Vatsiou, Alexandra, Graham, Trevor A., Élez, Elena, Argiles, Guillem, Nuciforo, Paolo, Sottoriva, Andrea, Dienstmann, Rodrigo, Pasini, Diego, Grassi, Elena, Isella, Claudio, Bertotti, Andrea, Trusolino, Livio
Vydáno v Sci Transl Med (2020)

Longitudinal liquid biopsy and mathematical modelling of clonal evolution forecast waiting time to treatment failure in the PROSPECT-C phase II colorectal cancer clinical trial

Autor Khan, Khurum H, Cunningham, David, Werner, Benjamin, Vlachogiannis, Georgios, Spiteri, Inmaculada, Heide, Timon, Mateos, Javier Fernandez, Vatsiou, Alexandra, Lampis, Andrea, Damavandi, Mahnaz Darvish, Lote, Hazel, Huntingford, Ian S., Hedayat, Somaieh, Chau, Ian, Tunariu, Nina, Mentrasti, Giulia, Trevisani, Francesco, Rao, Sheela, Anandappa, Gayathri, Watkins, David, Starling, Naureen, Thomas, Janet, Peckitt, Clare, Khan, Nasir, Rugge, Massimo, Begum, Ruwaida, Hezelova, Blanka, Bryant, Annette, Jones, Thomas, Proszek, Paula, Fassan, Matteo, Hahne, Jens C, Hubank, Michael, Braconi, Chiara, Sottoriva, Andrea, Valeri, Nicola
Vydáno v Cancer Discov (2018)