ChIPping away at gene regulation

Por Massie, Charles E, Mills, Ian G
Publicado em 2008

New androgen receptor genomic targets show an interaction with the ETS1 transcription factor

Por Massie, Charles E, Adryan, Boris, Barbosa-Morais, Nuno L, Lynch, Andy G, Tran, Maxine G, Neal, David E, Mills, Ian G
Publicado em 2007

Nongenetic stochastic expansion of JAK2V617F-homozygous subclones in polycythemia vera?

Por Godfrey, Anna L., Nangalia, Jyoti, Baxter, E. Joanna, Massie, Charles E., Kent, David G., Papaemmanuil, Elli, Campbell, Peter J., Green, Anthony R.
Publicado no Blood (2014)

Epigenetic and oncogenic regulation of SLC16A7 (MCT2) results in protein over-expression, impacting on signalling and cellular phenotypes in prostate cancer

Por Pertega-Gomes, Nelma, Vizcaino, Jose R., Felisbino, Sergio, Warren, Anne Y., Shaw, Greg, Kay, Jonathan, Whitaker, Hayley, Lynch, Andy G., Fryer, Lee, Neal, David E., Massie, Charles E.
Publicado no Oncotarget (2015)

HES5 silencing is an early and recurrent change in prostate tumourigenesis

Por Massie, Charles E, Spiteri, Inmaculada, Ross-Adams, Helen, Luxton, Hayley, Kay, Jonathan, Whitaker, Hayley C, Dunning, Mark J, Lamb, Alastair D, Ramos-Montoya, Antonio, Brewer, Daniel S, Cooper, Colin S, Eeles, Rosalind, Warren, Anne Y, Tavaré, Simon, Neal, David E, Lynch, Andy G
Publicado no Endocr Relat Cancer (2015)

STAT1 activation in association with JAK2 exon 12 mutations

Por Godfrey, Anna L., Chen, Edwin, Massie, Charles E., Silber, Yvonne, Pagano, Francesca, Bellosillo, Beatriz, Guglielmelli, Paola, Harrison, Claire N., Reilly, John T., Stegelmann, Frank, Bijou, Fontanet, Lippert, Eric, Boiron, Jean-Michel, Döhner, Konstanze, Vannucchi, Alessandro M., Besses, Carlos, Green, Anthony R.
Publicado no Haematologica (2016)

Implementing liquid biopsies into clinical decision making for cancer immunotherapy

Por Quandt, Dagmar, Zucht, Hans Dieter, Amann, Arno, Wulf-Goldenberg, Anne, Borrebaeck, Carl, Cannarile, Michael, Lambrechts, Diether, Oberacher, Herbert, Garrett, James, Nayak, Tapan, Kazinski, Michael, Massie, Charles, Schwarzenbach, Heidi, Maio, Michele, Prins, Robert, Wendik, Björn, Hockett, Richard, Enderle, Daniel, Noerholm, Mikkel, Hendriks, Hans, Zwierzina, Heinz, Seliger, Barbara
Publicado no Oncotarget (2017)

Inactivating CUX1 mutations promote tumorigenesis

Por Wong, Chi C., Martincorena, Inigo, Rust, Alistair G., Rashid, Mamunur, Alifrangis, Constantine, Alexandrov, Ludmil B., Tiffen, Jessamy C., Kober, Christina, Green, Anthony R., Massie, Charles E., Nangalia, Jyoti, Lempidaki, Stella, Döhner, Hartmut, Döhner, Konstanze, Bray, Sarah J., McDermott, Ultan, Papaemmanuil, Elli, Campbell, Peter J., Adams, David J.
Publicado em 2013

Effect of Mutation Order on Myeloproliferative Neoplasms

Por Ortmann, Christina A., Kent, David G., Nangalia, Jyoti, Silber, Yvonne, Wedge, David C., Grinfeld, Jacob, Baxter, E. Joanna, Massie, Charles E., Papaemmanuil, Elli, Menon, Suraj, Godfrey, Anna L., Dimitropoulou, Danai, Guglielmelli, Paola, Bellosillo, Beatriz, Besses, Carles, Döhner, Konstanze, Harrison, Claire N., Vassiliou, George S., Vannucchi, Alessandro, Campbell, Peter J., Green, Anthony R.
Publicado no N Engl J Med (2015)

The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis

Por Massie, Charles E, Lynch, Andy, Ramos-Montoya, Antonio, Boren, Joan, Stark, Rory, Fazli, Ladan, Warren, Anne, Scott, Helen, Madhu, Basetti, Sharma, Naomi, Bon, Helene, Zecchini, Vinny, Smith, Donna-Michelle, DeNicola, Gina M, Mathews, Nik, Osborne, Michelle, Hadfield, James, MacArthur, Stewart, Adryan, Boris, Lyons, Scott K, Brindle, Kevin M, Griffiths, John, Gleave, Martin E, Rennie, Paul S, Neal, David E, Mills, Ian G
Publicado em 2011

HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer

Por Ross-Adams, Helen, Ball, Stephen, Lawrenson, Kate, Halim, Silvia, Russell, Roslin, Wells, Claire, Strand, Siri H., Ørntoft, Torben F., Larson, Melissa, Armasu, Sebastian, Massie, Charles E., Asim, Mohammad, Mortensen, Martin M., Borre, Michael, Woodfine, Kathryn, Warren, Anne Y., Lamb, Alastair D., Kay, Jonathan, Whitaker, Hayley, Ramos-Montoya, Antonio, Murrell, Adele, Sørensen, Karina D., Fridley, Brooke L., Goode, Ellen L., Gayther, Simon A., Masters, John, Neal, David E., Mills, Ian G.
Publicado no Oncotarget (2016)

Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer

Por Asim, Mohammad, Tarish, Firas, Zecchini, Heather I., Sanjiv, Kumar, Gelali, Eleni, Massie, Charles E., Baridi, Ajoeb, Warren, Anne Y., Zhao, Wanfeng, Ogris, Christoph, McDuffus, Leigh-Anne, Mascalchi, Patrice, Shaw, Greg, Dev, Harveer, Wadhwa, Karan, Wijnhoven, Paul, Forment, Josep V., Lyons, Scott R., Lynch, Andy G., O’Neill, Cormac, Zecchini, Vincent R., Rennie, Paul S., Baniahmad, Aria, Tavaré, Simon, Mills, Ian G., Galanty, Yaron, Crosetto, Nicola, Schultz, Niklas, Neal, David, Helleday, Thomas
Publicado no Nat Commun (2017)

Comprehensive characterization of cell-free tumor DNA in plasma and urine of patients with renal tumors

Por Smith, Christopher G., Moser, Tina, Mouliere, Florent, Field-Rayner, Johanna, Eldridge, Matthew, Riediger, Anja L., Chandrananda, Dineika, Heider, Katrin, Wan, Jonathan C. M., Warren, Anne Y., Morris, James, Hudecova, Irena, Cooper, Wendy N., Mitchell, Thomas J., Gale, Davina, Ruiz-Valdepenas, Andrea, Klatte, Tobias, Ursprung, Stephan, Sala, Evis, Riddick, Antony C. P., Aho, Tevita F., Armitage, James N., Perakis, Samantha, Pichler, Martin, Seles, Maximilian, Wcislo, Gabriel, Welsh, Sarah J., Matakidou, Athena, Eisen, Tim, Massie, Charles E., Rosenfeld, Nitzan, Heitzer, Ellen, Stewart, Grant D.
Publicado no Genome Med (2020)

Enhanced detection of circulating tumor DNA by fragment size analysis

Por Mouliere, Florent, Chandrananda, Dineika, Piskorz, Anna M., Moore, Elizabeth K., Morris, James, Ahlborn, Lise Barlebo, Mair, Richard, Goranova, Teodora, Marass, Francesco, Heider, Katrin, Wan, Jonathan C. M., Supernat, Anna, Hudecova, Irena, Gounaris, Ioannis, Ros, Susana, Jimenez-Linan, Mercedes, Garcia-Corbacho, Javier, Patel, Keval, Østrup, Olga, Murphy, Suzanne, Eldridge, Matthew D., Gale, Davina, Stewart, Grant D., Burge, Johanna, Cooper, Wendy N., van der Heijden, Michiel S., Massie, Charles E., Watts, Colin, Corrie, Pippa, Pacey, Simon, Brindle, Kevin, Baird, Richard D., Mau-Sørensen, Morten, Parkinson, Christine A., Smith, Christopher G., Brenton, James D., Rosenfeld, Nitzan
Publicado no Sci Transl Med (2018)

Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target

Por Asim, Mohammad, Massie, Charles E., Orafidiya, Folake, Pértega-Gomes, Nelma, Warren, Anne Y., Esmaeili, Mohsen, Selth, Luke A., Zecchini, Heather I., Luko, Katarina, Qureshi, Arham, Baridi, Ajoeb, Menon, Suraj, Madhu, Basetti, Escriu, Carlos, Lyons, Scott, Vowler, Sarah L., Zecchini, Vincent R., Shaw, Greg, Hessenkemper, Wiebke, Russell, Roslin, Mohammed, Hisham, Stefanos, Niki, Lynch, Andy G., Grigorenko, Elena, D’Santos, Clive, Taylor, Chris, Lamb, Alastair, Sriranjan, Rouchelle, Yang, Jiali, Stark, Rory, Dehm, Scott M., Rennie, Paul S., Carroll, Jason S., Griffiths, John R., Tavaré, Simon, Mills, Ian G., McEwan, Iain J., Baniahmad, Aria, Tilley, Wayne D., Neal, David E.
Publicado no J Natl Cancer Inst (2015)

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

Por Ju, Young Seok, Alexandrov, Ludmil B, Gerstung, Moritz, Martincorena, Inigo, Nik-Zainal, Serena, Ramakrishna, Manasa, Davies, Helen R, Papaemmanuil, Elli, Gundem, Gunes, Shlien, Adam, Bolli, Niccolo, Behjati, Sam, Tarpey, Patrick S, Nangalia, Jyoti, Massie, Charles E, Butler, Adam P, Teague, Jon W, Vassiliou, George S, Green, Anthony R, Du, Ming-Qing, Unnikrishnan, Ashwin, Pimanda, John E, Teh, Bin Tean, Munshi, Nikhil, Greaves, Mel, Vyas, Paresh, El-Naggar, Adel K, Santarius, Tom, Collins, V Peter, Grundy, Richard, Taylor, Jack A, Hayes, D Neil, Malkin, David, Foster, Christopher S, Warren, Anne Y, Whitaker, Hayley C, Brewer, Daniel, Eeles, Rosalind, Cooper, Colin, Neal, David, Visakorpi, Tapio, Isaacs, William B, Bova, G Steven, Flanagan, Adrienne M, Futreal, P Andrew, Lynch, Andy G, Chinnery, Patrick F, McDermott, Ultan, Stratton, Michael R, Campbell, Peter J
Publicado no eLife (2014)