Pre-Clinical Assessment of Immune Responses to Adeno-Associated Virus (AAV) Vectors

Por Basner-Tschakarjan, Etiena, Bijjiga, Enoch, Martino, Ashley T.
Publicado em 2014

Measuring Immune Responses to recombinant AAV Gene Transfer

Por Martino, Ashley T., Herzog, Roland W., Anegon, Ignacio, Adjali, Oumeya
Publicado em 2011

Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B

Por Rogers, Geoffrey L, Martino, Ashley T, Zolotukhin, Irene, Ertl, Hildegund CJ, Herzog, Roland W
Publicado em 2014

Innate Immune Responses to AAV Vectors

Por Rogers, Geoffrey L., Martino, Ashley T., Aslanidi, George V., Jayandharan, Giridhara R., Srivastava, Arun, Herzog, Roland W.
Publicado em 2011

Nonredundant Roles of IL-10 and TGF-β in Suppression of Immune Responses to Hepatic AAV-Factor IX Gene Transfer

Por Hoffman, Brad E, Martino, Ashley T, Sack, Brandon K, Cao, Ou, Liao, Gongxian, Terhorst, Cox, Herzog, Roland W
Publicado em 2011

N-Glycosylation Augmentation of the Cystic Fibrosis Epithelium Improves Pseudomonas aeruginosa Clearance

Por Martino, Ashley T., Mueller, Christian, Braag, Sofia, Cruz, Pedro E., Campbell-Thompson, Martha, Jin, Shouguang, Flotte, Terence R.
Publicado em 2011

Activation of the NF-κB pathway by adeno-associated virus (AAV) vectors and its implications in immune response and gene therapy

Por Jayandharan, Giridhara R., Aslanidi, George, Martino, Ashley T., Jahn, Stephan C., Perrin, George Q., Herzog, Roland W., Srivastava, Arun
Publicado em 2011

Regulatory T cells and TLR9 Activation Shape Antibody Formation to a Secreted Transgene Product in AAV Muscle Gene Transfer

Por Herzog, Roland W., Cooper, Mario, Perrin, George Q., Biswas M, Moanaro, Martino, Ashley T., Morel, Laurence, Terhorst, Cox, Hoffman, Brad E.
Publicado no Cell Immunol (2017)

Tolerance Induction to Cytoplasmic β-Galactosidase by Hepatic AAV Gene Transfer — Implications for Antigen Presentation and Immunotoxicity

Por Martino, Ashley T., Nayak, Sushrusha, Hoffman, Brad E., Cooper, Mario, Liao, Gongxian, Markusic, David M., Byrne, Barry J., Terhorst, Cox, Herzog, Roland W.
Publicado em 2009

Recombinant AAV Serotype and Capsid Mutant Comparison for Pulmonary Gene Transfer of α-1-Antitrypsin Using Invasive and Noninvasive Delivery

Por Liqun Wang, Rejean, McLaughlin, Thomas, Cossette, Travis, Tang, Qiushi, Foust, Kevin, Campbell-Thompson, Martha, Martino, Ashley, Cruz, Pedro, Loiler, Scott, Mueller, Christian, Flotte, Terence R
Publicado em 2008

The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9–dependent innate immune responses in the liver

Por Martino, Ashley T., Suzuki, Masataka, Markusic, David M., Zolotukhin, Irene, Ryals, Renee C., Moghimi, Babak, Ertl, Hildegund C. J., Muruve, Daniel A., Lee, Brendan, Herzog, Roland W.
Publicado em 2011

Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8(+) T cells

Por Martino, Ashley T., Basner-Tschakarjan, Etiena, Markusic, David M., Finn, Jonathan D., Hinderer, Christian, Zhou, Shangzhen, Ostrov, David A., Srivastava, Arun, Ertl, Hildegund C. J., Terhorst, Cox, High, Katherine A., Mingozzi, Federico, Herzog, Roland W.
Publicado em 2013