N-Glycosylation Augmentation of the Cystic Fibrosis Epithelium Improves Pseudomonas aeruginosa Clearance

Chronic lung colonization with Pseudomonas aeruginosa is anticipated in cystic fibrosis (CF). Abnormal terminal glycosylation has been implicated as a candidate for this condition. We previously reported a down-regulation of mannose-6-phosphate isomerase (MPI) for core N-glycan production in the CFT...

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Bibliographic Details
Main Authors: Martino, Ashley T., Mueller, Christian, Braag, Sofia, Cruz, Pedro E., Campbell-Thompson, Martha, Jin, Shouguang, Flotte, Terence R.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2011
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135844/
https://ncbi.nlm.nih.gov/pubmed/20693405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0285OC
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