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Measuring Immune Responses to recombinant AAV Gene Transfer

Following AAV-based gene transfer, the occurrence of adaptive immune responses specific to the vector or the transgene product is a major roadblock to successful clinical translation. These responses include antibodies against the AAV capsid, which can be neutralizing and therefore prevent the abili...

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Detalhes bibliográficos
Main Authors: Martino, Ashley T., Herzog, Roland W., Anegon, Ignacio, Adjali, Oumeya
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593270/
https://ncbi.nlm.nih.gov/pubmed/22034034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-370-7_11
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