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Measuring Immune Responses to recombinant AAV Gene Transfer
Following AAV-based gene transfer, the occurrence of adaptive immune responses specific to the vector or the transgene product is a major roadblock to successful clinical translation. These responses include antibodies against the AAV capsid, which can be neutralizing and therefore prevent the abili...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593270/ https://ncbi.nlm.nih.gov/pubmed/22034034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-370-7_11 |
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