Cellular commitment to reentry into the cell cycle after stalled DNA is determined by site-specific phosphorylation of Chk1 and PTEN

Por Martin, Sarah A., Ouchi, Toru
Publicado no Mol Cancer Ther (2008)

DNA Mismatch Repair and Oxidative DNA Damage: Implications for Cancer Biology and Treatment

Por Bridge, Gemma, Rashid, Sukaina, Martin, Sarah A.
Publicado em 2014

The discovery and early structural studies of arachidonic acid

Por Martin, Sarah A., Brash, Alan R., Murphy, Robert C.
Publicado no J Lipid Res (2016)

Measurement of lysophospholipid acyltransferase activities using substrate competition

Por Martin, Sarah A., Gijón, Miguel A., Voelker, Dennis R., Murphy, Robert C.
Publicado em 2014

O06 TARGETING FOXM1 AS A NOVEL THERAPEUTIC STRATEGY FOR THE TREATMENT OF MSH6 DEFICIENT TEMOZOLOMIDE-RESISTANT GLIOBLASTOMA

Por Brierley, David J., Locke, Matthew, Merve, Ashirwad, Marino, Silvia, Martin, Sarah A.
Publicado em 2014

Maternal High-Fat Diet Worsens Memory Deficits in the Triple-Transgenic (3xTgAD) Mouse Model of Alzheimer’s Disease

Por Martin, Sarah A. L., Jameson, Christine H., Allan, Stuart M., Lawrence, Catherine B.
Publicado em 2014

Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2

Por Martin, Sarah A, McCarthy, Afshan, Barber, Louise J, Burgess, Darren J, Parry, Suzanne, Lord, Christopher J, Ashworth, Alan
Publicado em 2009

Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function

Por Grevengoed, Trisha J., Martin, Sarah A., Katunga, Lalage, Cooper, Daniel E., Anderson, Ethan J., Murphy, Robert C., Coleman, Rosalind A.
Publicado no J Lipid Res (2015)

Drug-repositioning screens identify Triamterene as a selective drug for the treatment of DNA Mismatch Repair deficient cells

Por Guillotin, Delphine, Austin, Philip, Begum, Rumena, Freitas, Marta O, Merve, Ashirwad, Brend, Tim, Short, Susan, Marino, Silvia, Martin, Sarah A
Publicado no Clin Cancer Res (2016)

Altered eicosanoid production and phospholipid remodeling during cell culture

Por Okuno, Toshiaki, Gijón, Miguel A., Zarini, Simona, Martin, Sarah A., Barkley, Robert M., Johnson, Christopher A., Ohba, Mai, Yokomizo, Takehiko, Murphy, Robert C.
Publicado no J Lipid Res (2018)

DNA Polymerases as Potential Therapeutic Targets for Cancers Deficient in the DNA Mismatch Repair Proteins MSH2 or MLH1

Por Martin, Sarah A., McCabe, Nuala, Mullarkey, Michelle, Cummins, Robert, Burgess, Darren J., Nakabeppu, Yusaku, Oka, Sugako, Kay, Elaine, Lord, Christopher J., Ashworth, Alan
Publicado em 2010

Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors

Por Mendes-Pereira, Ana M, Martin, Sarah A, Brough, Rachel, McCarthy, Afshan, Taylor, Jessica R, Kim, Jung-Sik, Waldman, Todd, Lord, Christopher J, Ashworth, Alan
Publicado em 2009

Inhibition of the Polyamine Synthesis Pathway Is Synthetically Lethal with Loss of Argininosuccinate Synthase 1

Por Locke, Matthew, Ghazaly, Essam, Freitas, Marta O., Mitsinga, Mikaella, Lattanzio, Laura, Lo Nigro, Cristiana, Nagano, Ai, Wang, Jun, Chelala, Claude, Szlosarek, Peter, Martin, Sarah A.
Publicado no Cell Rep (2016)

RAD51 and BRCA2 enhance oncolytic adenovirus type 5 activity in ovarian cancer

Por Tookman, Laura A., Browne, Ashley K., Connell, Claire M., Bridge, Gemma, Ingemarsdotter, Carin K., Dowson, Suzanne, Shibata, Atsushi, Lockley, Michelle, Martin, Sarah A., McNeish, Iain A.
Publicado no Mol Cancer Res (2015)

Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid

Por Sorgi, Carlos A., Zarini, Simona, Martin, Sarah A., Sanchez, Raphael L., Scandiuzzi, Rodrigo F., Gijón, Miguel A., Guijas, Carlos, Flamand, Nicolas, Murphy, Robert C., Faccioli, Lucia H.
Publicado no Sci Rep (2017)

Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma

Por Dawkins, Joshua B.N., Wang, Jun, Maniati, Eleni, Heward, James A., Koniali, Lola, Kocher, Hemant M., Martin, Sarah A., Chelala, Claude, Balkwill, Frances R., Fitzgibbon, Jude, Grose, Richard P.
Publicado no Cancer Res (2016)

Carbonic Anhydrase 9 Expression Increases with Vascular Endothelial Growth Factor–Targeted Therapy and Is Predictive of Outcome in Metastatic Clear Cell Renal Cancer

Por Stewart, Grant D., O’Mahony, Fiach C., Laird, Alexander, Rashid, Sukaina, Martin, Sarah A., Eory, Lel, Lubbock, Alexander L.R., Nanda, Jyoti, O’Donnell, Marie, Mackay, Alan, Mullen, Peter, McNeill, S. Alan, Riddick, Antony C.P., Aitchison, Michael, Berney, Daniel, Bex, Axel, Overton, Ian M., Harrison, David J., Powles, Thomas
Publicado no Eur Urol (2014)