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Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function
Long-chain acyl-CoA synthetase 1 (ACSL1) contributes more than 90% of total cardiac ACSL activity, but its role in phospholipid synthesis has not been determined. Mice with an inducible knockout of ACSL1 (Acsl1(T−/−)) have impaired cardiac fatty acid oxidation and rely on glucose for ATP production....
Guardat en:
| Publicat a: | J Lipid Res |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Biochemistry and Molecular Biology
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4513998/ https://ncbi.nlm.nih.gov/pubmed/26136511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M059717 |
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