Carbonic Anhydrase 9 Expression Increases with Vascular Endothelial Growth Factor–Targeted Therapy and Is Predictive of Outcome in Metastatic Clear Cell Renal Cancer

BACKGROUND: There is a lack of biomarkers to predict outcome with targeted therapy in metastatic clear cell renal cancer (mccRCC). This may be because dynamic molecular changes occur with therapy. OBJECTIVE: To explore if dynamic, targeted-therapy-driven molecular changes correlate with mccRCC outco...

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Опубликовано в: :Eur Urol
Главные авторы: Stewart, Grant D., O’Mahony, Fiach C., Laird, Alexander, Rashid, Sukaina, Martin, Sarah A., Eory, Lel, Lubbock, Alexander L.R., Nanda, Jyoti, O’Donnell, Marie, Mackay, Alan, Mullen, Peter, McNeill, S. Alan, Riddick, Antony C.P., Aitchison, Michael, Berney, Daniel, Bex, Axel, Overton, Ian M., Harrison, David J., Powles, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier Science 2014
Предметы:
From Lab to Clinic
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410300/
https://ncbi.nlm.nih.gov/pubmed/24821582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2014.04.007
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