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Overcoming intratumoural heterogeneity for reproducible molecular risk stratification: a case study in advanced kidney cancer

BACKGROUND: Metastatic clear cell renal cell cancer (mccRCC) portends a poor prognosis and urgently requires better clinical tools for prognostication as well as for prediction of response to treatment. Considerable investment in molecular risk stratification has sought to overcome the performance c...

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Detalhes bibliográficos
Publicado no:BMC Med
Main Authors: Lubbock, Alexander L. R., Stewart, Grant D., O’Mahony, Fiach C., Laird, Alexander, Mullen, Peter, O’Donnell, Marie, Powles, Thomas, Harrison, David J., Overton, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483837/
https://ncbi.nlm.nih.gov/pubmed/28648142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-017-0874-9
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