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Overcoming intratumoural heterogeneity for reproducible molecular risk stratification: a case study in advanced kidney cancer

BACKGROUND: Metastatic clear cell renal cell cancer (mccRCC) portends a poor prognosis and urgently requires better clinical tools for prognostication as well as for prediction of response to treatment. Considerable investment in molecular risk stratification has sought to overcome the performance c...

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Pubblicato in:BMC Med
Autori principali: Lubbock, Alexander L. R., Stewart, Grant D., O’Mahony, Fiach C., Laird, Alexander, Mullen, Peter, O’Donnell, Marie, Powles, Thomas, Harrison, David J., Overton, Ian M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483837/
https://ncbi.nlm.nih.gov/pubmed/28648142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-017-0874-9
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