Dynamic epigenetic changes to VHL occur with sunitinib in metastatic clear cell renal cancer

BACKGROUND: Genetic intratumoral heterogeneity (ITH) hinders biomarker development in metastatic clear cell renal cancer (mccRCC). Epigenetic relative to genetic ITH or the presence of consistent epigenetic changes following targeted therapy in mccRCC have not been evaluated. The aim of this study w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Stewart, Grant D., Powles, Thomas, Van Neste, Christophe, Meynert, Alison, O'Mahony, Fiach, Laird, Alexander, Deforce, Dieter, Van Nieuwerburgh, Filip, Trooskens, Geert, Van Criekinge, Wim, De Meyer, Tim, Harrison, David J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2016
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041900/
https://ncbi.nlm.nih.gov/pubmed/27029034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8308
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