Overcoming intratumoural heterogeneity for reproducible molecular risk stratification: a case study in advanced kidney cancer

BACKGROUND: Metastatic clear cell renal cell cancer (mccRCC) portends a poor prognosis and urgently requires better clinical tools for prognostication as well as for prediction of response to treatment. Considerable investment in molecular risk stratification has sought to overcome the performance c...

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Vydáno v:BMC Med
Hlavní autoři: Lubbock, Alexander L. R., Stewart, Grant D., O’Mahony, Fiach C., Laird, Alexander, Mullen, Peter, O’Donnell, Marie, Powles, Thomas, Harrison, David J., Overton, Ian M.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483837/
https://ncbi.nlm.nih.gov/pubmed/28648142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-017-0874-9
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