Therapeutic applications of trans-splicing

по Hong, Elizabeth M, Ingemarsdotter, Carin K, Lever, Andrew M L
Опубликовано в: Br Med Bull (2020)

Expression of Herpes Simplex Virus Thymidine Kinase/Ganciclovir by RNA Trans-Splicing Induces Selective Killing of HIV-Producing Cells

по Ingemarsdotter, Carin K., Poddar, Sushmita, Mercier, Sarah, Patzel, Volker, Lever, Andrew M.L.
Опубликовано в: Mol Ther Nucleic Acids (2017)

A scale-free analysis of the HIV-1 genome demonstrates multiple conserved regions of structural and functional importance

по Skittrall, Jordan P., Ingemarsdotter, Carin K., Gog, Julia R., Lever, Andrew M. L.
Опубликовано в: PLoS Comput Biol (2019)

An RNA-binding compound that stabilizes the HIV-1 gRNA packaging signal structure and specifically blocks HIV-1 RNA encapsidation

по Ingemarsdotter, Carin K., Zeng, Jingwei, Long, Ziqi, Lever, Andrew M.L., Kenyon, Julia C.
Опубликовано в: Retrovirology (2018)

Pharmacological inhibition of β3 integrin reduces the inflammatory toxicities caused by oncolytic adenovirus without compromising anticancer activity

по Browne, Ashley, Tookman, Laura A., Ingemarsdotter, Carin K., Bouwman, Russell D., Pirlo, Katrina, Wang, Yaohe, McNeish, Iain A., Lockley, Michelle
Опубликовано в: Cancer Res (2015)

Inhibition of the Inflammatory Cytokine TNF-α Increases Adenovirus Activity in Ovarian Cancer via Modulation of cIAP1/2 Expression

по Salako, Michael A, Kulbe, Hagen, Ingemarsdotter, Carin K, Pirlo, Katrina J, Williams, Sarah L, Lockley, Michelle, Balkwill, Frances R, McNeish, Iain A
Опубликовано 2011

RAD51 and BRCA2 enhance oncolytic adenovirus type 5 activity in ovarian cancer

по Tookman, Laura A., Browne, Ashley K., Connell, Claire M., Bridge, Gemma, Ingemarsdotter, Carin K., Dowson, Suzanne, Shibata, Atsushi, Lockley, Michelle, Martin, Sarah A., McNeish, Iain A.
Опубликовано в: Mol Cancer Res (2015)

Paclitaxel resistance increases oncolytic adenovirus efficacy via upregulated CAR expression and dysfunctional cell cycle control

по Ingemarsdotter, Carin K., Tookman, Laura A., Browne, Ashley, Pirlo, Katrina, Cutts, Rosalind, Chelela, Claude, Khurrum, Karisma F., Leung, Elaine Y.L., Dowson, Suzanne, Webber, Lee, Khan, Iftekhar, Ennis, Darren, Syed, Nelofer, Crook, Tim R., Brenton, James D., Lockley, Michelle, McNeish, Iain A.
Опубликовано в: Mol Oncol (2014)