Transforming growth factor-beta and mutant p53 conspire to induce metastasis by antagonizing p63: a (ternary) complex affair

Por Marine, Jean-Christophe, Berx, Geert
Publicado em 2009

NEAT1-containing paraspeckles: Central hubs in stress response and tumor formation

Por Adriaens, Carmen, Marine, Jean-Christophe
Publicado no Cell Cycle (2016)

MDMX (MDM4), a Promising Target for p53 Reactivation Therapy and Beyond

Por Marine, Jean-Christophe, Jochemsen, Aart G.
Publicado no Cold Spring Harb Perspect Med (2016)

IGF2: The Achilles' heel of p53-deficiency?

Por Clermont, Frederic, Nittner, David, Marine, Jean-Christophe
Publicado em 2012

Suppression of Myc oncogenic activity by Nucleostemin haploinsufficiency

Por Zwolinska, Aleksandra K., Whiting, Amy Heagle, Beekman, Chantal, Sedivy, John, Marine, Jean-Christophe
Publicado em 2011

Monoallelic but not bialleleic loss of Dicer1 promotes tumorigenesis in vivo

Por Lambertz, Irina, Nittner, David, Mestdagh, Pieter, Denecker, Geertrui, Vandesompele, Jo, Dyer, Mike A., Marine, Jean-Christophe
Publicado em 2009

The Ornithine Decarboxylase Gene Is Essential for Cell Survival during Early Murine Development

Por Pendeville, Hélène, Carpino, Nick, Marine, Jean-Christophe, Takahashi, Yutaka, Muller, Marc, Martial, Joseph A., Cleveland, John L.
Publicado em 2001

Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression

Por Benavente, Claudia A., Finkelstein, David, Johnson, Dianna A., Marine, Jean-Christophe, Ashery-Padan, Ruth, Dyer, Michael A.
Publicado no Oncotarget (2014)

Critical Role for a Central Part of Mdm2 in the Ubiquitylation of p53

Por Meulmeester, Erik, Frenk, Ruth, Stad, Robert, de Graaf, Petra, Marine, Jean-Christophe, Vousden, Karen H., Jochemsen, Aart G.
Publicado em 2003

A small amphipathic α-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5

Por Wang, Demin, Moriggl, Richard, Stravopodis, Dimitrios, Carpino, Nick, Marine, Jean–Christophe, Teglund, Stephan, Feng, Jian, Ihle, James N.
Publicado em 2000

Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation

Por Kieslinger, Matthias, Woldman, Irina, Moriggl, Richard, Hofmann, Johannes, Marine, Jean-Christophe, Ihle, James N., Beug, Hartmut, Decker, Thomas
Publicado em 2000

Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo

Por Francoz, Sarah, Froment, Pascal, Bogaerts, Sven, De Clercq, Sarah, Maetens, Marion, Doumont, Gilles, Bellefroid, Eric, Marine, Jean-Christophe
Publicado em 2006

Evolutionarily Conserved Role of Nucleostemin: Controlling Proliferation of Stem/Progenitor Cells during Early Vertebrate Development

Por Beekman, Chantal, Nichane, Massimo, De Clercq, Sarah, Maetens, Marion, Floss, Thomas, Wurst, Wolfgang, Bellefroid, Eric, Marine, Jean-Christophe
Publicado em 2006

The long noncoding RNA Neat1 is required for mammary gland development and lactation

Por Standaert, Laura, Adriaens, Carmen, Radaelli, Enrico, Van Keymeulen, Alexandra, Blanpain, Cedric, Hirose, Tetsuro, Nakagawa, Shinichi, Marine, Jean-Christophe
Publicado no RNA (2014)

Widespread Overexpression of Epitope-Tagged Mdm4 Does Not Accelerate Tumor Formation In Vivo

Por De Clercq, Sarah, Gembarska, Agnieszka, Denecker, Geertrui, Maetens, Marion, Naessens, Michael, Haigh, Katharina, Haigh, Jody J., Marine, Jean-Christophe
Publicado em 2010

Loss of autocrine endothelial-derived VEGF significantly reduces hemangiosarcoma development in conditional p53-deficient mice

Por Farhang Ghahremani, Morvarid, Radaelli, Enrico, Haigh, Katharina, Bartunkova, Sonia, Haenebalcke, Lieven, Marine, Jean-Christophe, Goossens, Steven, Haigh, Jody J
Publicado em 2014

Spontaneous Post-Transplant Disorders in NOD.Cg- Prkdc(scid) Il2rg(tm1Sug)/JicTac (NOG) Mice Engrafted with Patient-Derived Metastatic Melanomas

Por Radaelli, Enrico, Hermans, Els, Omodho, Lorna, Francis, Annick, Vander Borght, Sara, Marine, Jean-Christophe, van den Oord, Joost, Amant, Frédéric
Publicado no PLoS One (2015)

Mdm4 (Mdmx) Regulates p53-Induced Growth Arrest and Neuronal Cell Death during Early Embryonic Mouse Development

Por Migliorini, Domenico, Denchi, Eros Lazzerini, Danovi, Davide, Jochemsen, Aart, Capillo, Manuela, Gobbi, Alberto, Helin, Kristian, Pelicci, Pier Giuseppe, Marine, Jean-Christophe
Publicado em 2002

Nucleophosmin Is Required for DNA Integrity and p19(Arf) Protein Stability

Por Colombo, Emanuela, Bonetti, Paola, Lazzerini Denchi, Eros, Martinelli, Paola, Zamponi, Raffaella, Marine, Jean-Christophe, Helin, Kristian, Falini, Brunangelo, Pelicci, Pier Giuseppe
Publicado em 2005

The lncRNA Neat1 is required for corpus luteum formation and the establishment of pregnancy in a subpopulation of mice

Por Nakagawa, Shinichi, Shimada, Masayuki, Yanaka, Kaori, Mito, Mari, Arai, Takashi, Takahashi, Eiki, Fujita, Youko, Fujimori, Toshihiko, Standaert, Laura, Marine, Jean-Christophe, Hirose, Tetsuro
Publicado no Development (2014)