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Monoallelic but not bialleleic loss of Dicer1 promotes tumorigenesis in vivo
Human tumors are characterized by widespread reduction in microRNA (miRNA) expression [1], although it is unclear how such changes come about and whether they have an etiological role in the disease. Importantly, miRNA-knockdown has been shown to enhance the tumorigenic potential of human lung adeno...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892162/ https://ncbi.nlm.nih.gov/pubmed/20019750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.202 |
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