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MDMX (MDM4), a Promising Target for p53 Reactivation Therapy and Beyond
The MDMX protein was identified as a p53-interacting protein with a strong similarity to MDM2. Like Mdm2, Mdmx expression is essential for curbing p53 activity during embryonic development, indicating nonredundant functions of Mdmx and Mdm2. There is now a large body of evidence indicating that canc...
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| Pubblicato in: | Cold Spring Harb Perspect Med |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4930919/ https://ncbi.nlm.nih.gov/pubmed/27371671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026237 |
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