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Suppression of Myc oncogenic activity by Nucleostemin haploinsufficiency
Nucleostemin (NS) encodes a nucleolar GTPase which is highly expressed in stem/progenitor cells and in most cancer cells. However, little is known about the regulation of NS expression. Here we identify NS as a novel direct transcriptional target of the c-Myc oncoprotein. We show that Myc overexpres...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370078/ https://ncbi.nlm.nih.gov/pubmed/22081066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.507 |
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