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Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency

The Myc oncogene regulates the expression of multiple components of the protein synthetic machinery, including ribosomal proteins, initiation factors of translation, Pol III, and rDNA1,2. An outstanding question is whether and how increasing the cellular protein synthesis capacity can affect the mul...

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Bibliografische gegevens
Hoofdauteurs: Barna, Maria, Pusic, Aya, Zollo, Ornella, Costa, Maria, Kondrashov, Nadya, Rego, Eduardo, Rao, Pulivarthi H, Ruggero, Davide
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880952/
https://ncbi.nlm.nih.gov/pubmed/19011615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07449
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