Suppression of Aurora-A oncogenic potential by c-Myc downregulation

The abnormality of serine/threonine kinase Aurora-A is seen in many types of cancers. Although in physiological context it has been shown to play a vital role in cellular mitosis, how this oncogene contributes to tumorigenesis remains unclear. Here we demonstrate that Aurora-A overexpression enhance...

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Bibliografiske detaljer
Main Authors: Yang, Shangbin, He, Shun, Zhou, Xiaobo, Liu, Mei, Zhu, Hongxia, Wang, Yihua, Zhang, Wei, Yan, Shuang, Quan, Lanping, Bai, Jingfeng, Xu, Ningzhi
Format: Artigo
Sprog:Inglês
Udgivet: Korean Society for Biochemistry and Molecular Biology 2010
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992855/
https://ncbi.nlm.nih.gov/pubmed/20890087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.11.077
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