P21-Activated Kinase 7 Mediates Cisplatin-Resistance of Esophageal Squamous Carcinoma Cells with Aurora-A Overexpression

Aurora-A overexpression is common in various types of cancers and has been shown to be involved in tumorigenesis through different signaling pathways, yet how the deregulation affects cancer therapeutics remains elusive. Here we showed that overexpression of Aurora-A rendered esophageal cancer cells...

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Vydáno v:PLoS One
Hlavní autoři: He, Shun, Feng, Min, Liu, Mei, Yang, Shangbin, Yan, Shuang, Zhang, Wei, Wang, Zaozao, Hu, Chenfei, Xu, Qing, Chen, Lechuang, Zhu, Hongxia, Xu, Ningzhi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250179/
https://ncbi.nlm.nih.gov/pubmed/25436453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113989
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