Overexpression of KLF4 promotes cell senescence through microRNA-203-survivin-p21 pathway

Krüppel-like factor 4 (KLF4) is a transcription factor and functions as a tumor suppressor or tumor promoter in different cancer types. KLF4 regulates many gene expression, thus affects the process of cell proliferation, differentiation, and apoptosis. Recently, KLF4 was reported to induce senescenc...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Xu, Qing, Liu, Mei, Zhang, Ju, Xue, Liyan, Zhang, Guo, Hu, Chenfei, Wang, Zaozao, He, Shun, Chen, Lechuang, Ma, Kai, Liu, Xianghe, Zhao, Yahui, Lv, Ning, Liang, Shufang, Zhu, Hongxia, Xu, Ningzhi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312384/
https://ncbi.nlm.nih.gov/pubmed/27531889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11200
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