Polarization of macrophages in the tumor microenvironment is influenced by EGFR signaling within colon cancer cells

Epidermal growth factor receptor (EGFR) is a target of colon cancer therapy, but the effects of this therapy on the tumor microenvironment remain poorly understood. Our in vivo studies showed that cetuximab, an anti-EGFR monoclonal antibody, effectively inhibited AOM/DSS-induced, colitis-associated...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Zhang, Weina, Chen, Lechuang, Ma, Kai, Zhao, Yahui, Liu, Xianghe, Wang, Yu, Liu, Mei, Liang, Shufang, Zhu, Hongxia, Xu, Ningzhi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342747/
https://ncbi.nlm.nih.gov/pubmed/27683110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12207
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