Inhibition of survivin enhances radiosensitivity of esophageal cancer cells by switching radiation-induced senescence to apoptosis

PURPOSE: Strategies to increase radiosensitivity are urgently needed. Combining radiosensitizing reagents with radiotherapy could improve the outcome of cancer treatment. Some preclinical studies showed that sepantronium bromide (YM155) could sensitize cancer cells to radiation by inhibiting the sur...

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Bibliografiske detaljer
Udgivet i:Onco Targets Ther
Main Authors: Liu, Xianghe, Zhao, Yahui, Zhang, Weina, Gao, Yang, Huo, Miaomiao, Liu, Mei, Xiao, Zefen, Liang, Shufang, Xu, Ningzhi, Zhu, Hongxia
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975611/
https://ncbi.nlm.nih.gov/pubmed/29872320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S166798
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