Inhibition of survivin enhances radiosensitivity of esophageal cancer cells by switching radiation-induced senescence to apoptosis

PURPOSE: Strategies to increase radiosensitivity are urgently needed. Combining radiosensitizing reagents with radiotherapy could improve the outcome of cancer treatment. Some preclinical studies showed that sepantronium bromide (YM155) could sensitize cancer cells to radiation by inhibiting the sur...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Liu, Xianghe, Zhao, Yahui, Zhang, Weina, Gao, Yang, Huo, Miaomiao, Liu, Mei, Xiao, Zefen, Liang, Shufang, Xu, Ningzhi, Zhu, Hongxia
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975611/
https://ncbi.nlm.nih.gov/pubmed/29872320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S166798
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