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Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency

The Myc oncogene regulates the expression of multiple components of the protein synthetic machinery, including ribosomal proteins, initiation factors of translation, Pol III, and rDNA1,2. An outstanding question is whether and how increasing the cellular protein synthesis capacity can affect the mul...

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Detalhes bibliográficos
Main Authors: Barna, Maria, Pusic, Aya, Zollo, Ornella, Costa, Maria, Kondrashov, Nadya, Rego, Eduardo, Rao, Pulivarthi H, Ruggero, Davide
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880952/
https://ncbi.nlm.nih.gov/pubmed/19011615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07449
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