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Spontaneous Post-Transplant Disorders in NOD.Cg- Prkdc(scid) Il2rg(tm1Sug)/JicTac (NOG) Mice Engrafted with Patient-Derived Metastatic Melanomas

Patient-derived tumor xenograft (PDTX) approach is nowadays considered a reliable preclinical model to study in vivo cancer biology and therapeutic response. NOD scid and Il2rg-deficient mice represent the “gold standard” host for the generation of PDTXs. Compared to other immunocompromised murine l...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Radaelli, Enrico, Hermans, Els, Omodho, Lorna, Francis, Annick, Vander Borght, Sara, Marine, Jean-Christophe, van den Oord, Joost, Amant, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440639/
https://ncbi.nlm.nih.gov/pubmed/25996609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124974
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