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Spontaneous Post-Transplant Disorders in NOD.Cg- Prkdc(scid) Il2rg(tm1Sug)/JicTac (NOG) Mice Engrafted with Patient-Derived Metastatic Melanomas
Patient-derived tumor xenograft (PDTX) approach is nowadays considered a reliable preclinical model to study in vivo cancer biology and therapeutic response. NOD scid and Il2rg-deficient mice represent the “gold standard” host for the generation of PDTXs. Compared to other immunocompromised murine l...
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Publicado no: | PLoS One |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4440639/ https://ncbi.nlm.nih.gov/pubmed/25996609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124974 |
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