Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression

The retinoblastoma (Rb) family of proteins are key regulators of cell cycle exit during development and their deregulation is associated with cancer. Rb is critical for normal retinal development and germline mutations lead to retinoblastoma making retinae an attractive system to study Rb family sig...

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Foilsithe in:Oncotarget
Main Authors: Benavente, Claudia A., Finkelstein, David, Johnson, Dianna A., Marine, Jean-Christophe, Ashery-Padan, Ruth, Dyer, Michael A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2014
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Priority Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259422/
https://ncbi.nlm.nih.gov/pubmed/25338120
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