Radical SAM enzymes involved in RiPP biosynthesis

Autor Mahanta, Nilkamal, Hudson, Graham A., Mitchell, Douglas A.
Vydáno v Biochemistry (2017)

Reconstitution and substrate specificity of the thioether-forming radical S-adenosylmethionine enzyme in freyrasin biosynthesis

Autor Precord, Timothy W., Mahanta, Nilkamal, Mitchell, Douglas A.
Vydáno v ACS Chem Biol (2019)

Menaquinone Biosynthesis: Formation of aminofutalosine requires a unique radical SAM enzyme

Autor Mahanta, Nilkamal, Fedoseyenko, Dmytro, Dairi, Tohru, Begley, Tadhg P.
Vydáno 2013

Pseudouridine Monophosphate Glycosidase: a New Glycosidase Mechanism(,)

Autor Huang, Siyu, Mahanta, Nilkamal, Begley, Tadhg P., Ealick, Steven E.
Vydáno 2012

Measurement of Kinetics and Active Site Distances in Metalloenzyme Using Paramagnetic NMR with (13)C Hyperpolarization

Autor Liu, Mengxiao, Zhang, Guannan, Mahanta, Nilkamal, Lee, Youngbok, Hilty, Christian
Vydáno v J Phys Chem Lett (2018)

Post-translational thioamidation of methyl-coenzyme M reductase, a key enzyme in methanogenic and methanotrophic Archaea

Autor Nayak, Dipti D, Mahanta, Nilkamal, Mitchell, Douglas A, Metcalf, William W
Vydáno v eLife (2017)

Thioamides: Biosynthesis of Natural Compounds and Chemical Applications

Autor Mahanta, Nilkamal, Szantai-Kis, Miklos, Petersson, E. James, Mitchell, Douglas A.
Vydáno v ACS Chem Biol (2019)

Performance study of a sterilization box using a combination of heat and ultraviolet light irradiation for the prevention of COVID-19

Autor Mahanta, Nilkamal, Saxena, Varun, Pandey, Lalit M., Batra, Priyanka, Dixit, U.S.
Vydáno v Environ Res (2021)

Enzymatic reconstitution of ribosomal peptide backbone thioamidation

Autor Mahanta, Nilkamal, Liu, Andi, Dong, Shihui, Nair, Satish K., Mitchell, Douglas A.
Vydáno v Proc Natl Acad Sci U S A (2018)

Enzymatic thioamidation of peptide backbones

Autor Liu, Andi, Krushnamurthy, P. H., Subramanya, K. S., Mitchell, Douglas A., Mahanta, Nilkamal
Vydáno v Methods Enzymol (2021)

Mechanistic Basis for Ribosomal Peptide Backbone Modifications

Autor Dong, Shi-Hui, Liu, Andi, Mahanta, Nilkamal, Mitchell, Douglas A., Nair, Satish K.
Vydáno v ACS Cent Sci (2019)

Reconstitution and substrate specificity of the radical SAM thiazole C-methyltransferase in thiomuracin biosynthesis

Autor Mahanta, Nilkamal, Zhang, Zhengan, Hudson, Graham A., van der Donk, Wilfred A., Mitchell, Douglas A.
Vydáno v J Am Chem Soc (2017)

Mechanism of a Class C Radical S-Adenosyl-l-methionine Thiazole Methyl Transferase

Autor Zhang, Zhengan, Mahanta, Nilkamal, Hudson, Graham A., Mitchell, Douglas A., van der Donk, Wilfred A.
Vydáno v J Am Chem Soc (2017)

Antiproliferative and Proapoptotic Activities of Marine Sponge Hyrtios erectus Extract on Breast Carcinoma Cell Line (MCF-7)

Autor Muthiyan, Ramachandran, Nambikkairaj, Balwin, Mahanta, Nilkamal, Immanuel, Titus, Mandal, Rahul Shubhra, Kumaran, Kubendiran, De, Arun Kumar
Vydáno v Pharmacogn Mag (2017)

In vitro biosynthetic studies of bottromycin expand the enzymatic capabilities of the YcaO superfamily

Autor Schwalen, Christopher J., Hudson, Graham A., Kosol, Simone, Mahanta, Nilkamal, Challis, Gregory L., Mitchell, Douglas A.
Vydáno v J Am Chem Soc (2017)

Antibacterial Strategy against H. pylori: Inhibition of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis

Autor Joshi, Sumedh, Fedoseyenko, Dmytro, Mahanta, Nilkamal, Ducati, Rodrigo G., Feng, Mu, Schramm, Vern L., Begley, Tadhg P.
Vydáno v ACS Med Chem Lett (2019)

Biosynthetic timing and substrate specificity for the thiopeptide thiomuracin

Autor Zhang, Zhengan, Hudson, Graham A., Mahanta, Nilkamal, Tietz, Jonathan I., van der Donk, Wilfred A., Mitchell, Douglas A.
Vydáno v J Am Chem Soc (2016)

Functional Elucidation of TfuA in Peptide Backbone Thioamidation

Autor Liu, Andi, Si, Yuanyuan, Dong, Shi-Hui, Mahanta, Nilkamal, Penkala, Haley N., Nair, Satish K., Mitchell, Douglas A.
Vydáno v Nat Chem Biol (2021)

Radical S-Adenosylmethionine (SAM) Enzymes in Cofactor Biosynthesis: A Treasure Trove of Complex Organic Radical Rearrangement Reactions

Autor Mehta, Angad P., Abdelwahed, Sameh H., Mahanta, Nilkamal, Fedoseyenko, Dmytro, Philmus, Benjamin, Cooper, Lisa E., Liu, Yiquan, Jhulki, Isita, Ealick, Steven E., Begley, Tadhg P.
Vydáno v J Biol Chem (2015)

A Natural Quinazoline Derivative from Marine Sponge Hyrtios erectus Induces Apoptosis of Breast Cancer Cells via ROS Production and Intrinsic or Extrinsic Apoptosis Pathways

Autor De, Arun Kumar, Muthiyan, Ramachandran, Mondal, Samiran, Mahanta, Nilkamal, Bhattacharya, Debasis, Ponraj, Perumal, Muniswamy, Kangayan, Kundu, Anandamoy, Kundu, Madhu Sudhan, Sunder, Jai, Karunakaran, Dhanasekar, Bera, Asit Kumar, Roy, Sibnarayan Dam, Malakar, Dhruba
Vydáno v Mar Drugs (2019)