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Mechanistic Basis for Ribosomal Peptide Backbone Modifications

[Image: see text] YcaO enzymes are known to catalyze the ATP-dependent formation of azoline heterocycles, thioamides, and (macro)lactamidines on peptide substrates. These enzymes are found in multiple biosynthetic pathways, including those for several different classes of ribosomally synthesized and...

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Detalhes bibliográficos
Publicado no:ACS Cent Sci
Main Authors: Dong, Shi-Hui, Liu, Andi, Mahanta, Nilkamal, Mitchell, Douglas A., Nair, Satish K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535971/
https://ncbi.nlm.nih.gov/pubmed/31139720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.9b00124
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