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Molecular Basis for Autocatalytic Backbone N-Methylation in RiPP Natural Product Biosynthesis

N-Methylation of nucleic acids, proteins and peptides is a chemical modification with significant impact on biological regulation. Despite the simplicity of the structural change, N-methylation can influence diverse functions including epigenetics, protein complex formation, and microtubule stabilit...

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Bibliographic Details
Published in:ACS Chem Biol
Main Authors: Ongpipattanakul, Chayanid, Nair, Satish K.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340302/
https://ncbi.nlm.nih.gov/pubmed/30204409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00668
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