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Steric complementarity directs sequence promiscuous leader binding in RiPP biosynthesis

Enzymes that generate ribosomally synthesized and posttranslationally modified peptide (RiPP) natural products have garnered significant interest, given their ability to produce large libraries of chemically diverse scaffolds. Such RiPP biosynthetic enzymes are predicted to bind their corresponding...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Chekan, Jonathan R., Ongpipattanakul, Chayanid, Nair, Satish K.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883790/
https://ncbi.nlm.nih.gov/pubmed/31719203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908364116
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